• 1000 mg almasilate

• caramel flavor
• Sodium saccharine
• Povidone K25
• water, purified
• Hyetellosis
• 1100 mg propylene glycol
• 320 mg sorbitol

indication Duodenal ulcer, heartburn, MEGALAC Almasilate Suspension

• The drug is an agent for binding excess stomach acid (antacid).
• The drug is used for the symptomatic treatment of diseases in which the stomach acid is to be bound:
  • Gastric and duodenal ulcers
  • Heartburn and acid-related stomach problems

Duodenal ulcer, heartburn, MEGALAC Almasilate Suspension dosage

• Always take this medicine exactly as described or as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.
  • Unless otherwise prescribed by the doctor, the usual dose is:
    • Unless otherwise prescribed, take 10 ml of the medicine (= 1 sachet) 4 times a day.
• Use in children and adolescents
  • The drug should not be used in children under 12 years of age, as there is insufficient experience in this age group.

• duration of use
  • The duration of treatment depends on the type and severity as well as the course of the disease.
  • If the symptoms persist during treatment for more than 2 weeks, a doctor should be consulted.
  • Please talk to your doctor or pharmacist if you have the impression that the effect of the medicine is too strong or too weak.

• If you take more of the medicine than you should
  • Poisoning with the drug is not known or expected.
  • Overdosing can lead to changes in stool behavior such as softening of the stool and increased frequency of stools.
  • Therapeutic measures are generally not required here.

• If you forget to take a dose
  • Do not take a double dose to make up for a forgotten dose.

• If you stop taking it
  • In any case, talk to your doctor before you - e.g. B. due to the occurrence of side effects - arbitrarily interrupt the treatment with the drug or end it prematurely.

• If you have any further questions on the use of the medicine, ask your doctor or pharmacist.

Duodenal ulcer, heartburn, MEGALAC Almasilate Suspension way

• To take.
• It should be taken undiluted 1-2 hours after meals and before bedtime.

side effects

• Like all medicines, this can cause side effects, although not everyone gets them.
• The frequency of side effects is based on the following categories:
  • Very common: affects more than 1 in 10 people
  • Common: affects 1 to 10 users in 100
  • Uncommon: affects 1 to 10 users in 1,000
  • Rare: affects 1 to 10 users in 10,000
  • Very rare: affects less than 1 in 10,000 people
  • Not known: frequency cannot be estimated from the available data
• Possible side effects:
  • Immune system disorders:
    • Rare: Hypersensitivity reactions.
  • Diseases of the gastrointestinal tract:
    • Frequency not known: high doses can cause gastrointestinal problems such as mushy stools, constipation, flatulence and a feeling of fullness.
  • Diseases of the kidneys and urinary tract:
    • Very rare: Silicate stones in the kidneys or bladder during long-term therapy.
• If you have severely reduced kidney function, taking medicines containing magnesium and aluminum such as this medicine can cause increased levels of magnesium in the blood (hypermagnesaemia) and an increase in serum aluminum levels.
• In the case of insufficient renal performance (renal insufficiency) and long-term intake of high doses, aluminum deposits, especially in the nerve and bone tissue, and phosphate depletion as well as an increased magnesium level in the blood up to symptoms of poisoning by magnesium, which are caused by central nervous disorders, muscle weakness, reflex failures, can occur , fatigue, symptoms of paralysis, unconsciousness and cardiac arrhythmia.
• The aluminum blood levels should be checked regularly during long-term use and not exceed 40 µg/l.
• Countermeasures for side effects:
  • The dose should be reduced if there are problems in the gastrointestinal area. In the case of other side effects, the intake should be stopped and a doctor should be consulted.
• If you get any side effects, talk to your doctor or pharmacist. This also applies to side effects that are not specified.

Duodenal ulcer, heartburn, MEGALAC Almasilate Suspension interactions

• Taking with other medicines
  • Tell your doctor or pharmacist if you are taking/using, have recently taken/used or might take/use any other medicines.
  • The absorption and thus the effectiveness of other medicines are reduced by the medicine. This is particularly important with certain antibiotics (e.g. tetracyclines and quinolone derivatives such as ciprofloxacin, ofloxacin, norfloxacin, trovafloxacin) and with drugs that increase heart strength (cardiac glycosides). A reduction in the intake of the following drugs has also been described: halofantrine (malaria drug), phenytoin (epilepsy drug), H ₂ -receptor blockers of the cimetidine type, ranitidine (agent against gastric and intestinal ulcers), beta-blockers such as propranolol; Sotalol (hypertensive medicine). In contrast, an increase in absorption of levodopa (Parkinson's drug) was observed.
  • Alkalinization of the urine during therapy can affect the excretion of some drugs. This can e.g. B. lead to a decrease in salicylate levels or an increase in quinidine levels.
  • Therefore, other medicines should be taken 1-2 hours before or after taking this medicine.
• Take with food and drink
  • Concomitant use of this drug and acidic drinks (fruit juices, wine) leads to an undesirable increase in the absorption of aluminum from the intestine. Effervescent tablets also contain fruit acids, which can increase aluminum intake.

Contraindications

• The drug must not be taken
  • if you are allergic to almasilate or any of the other ingredients of this medicine,
  • if you have a reduced phosphate concentration in the blood (hypophosphataemia).
• Children and young people under the age of 12
  • The drug should not be used in children under 12 years of age, as there is insufficient experience in this age group.

pregnancy and breast feeding period

• If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
• pregnancy
  • The risk-benefit balance should be carefully considered before taking aluminum-containing antacids during pregnancy. The drug should only be used for a short time during pregnancy in order to avoid exposure of the child to aluminum.
• lactation
  • Aluminum compounds pass into breast milk. A risk for the newborn cannot be assumed, since only very small amounts are absorbed.

patient Duodenal ulcer, heartburn, MEGALAC Almasilate Suspension notes

• Warnings and Precautions
  • Please talk to your doctor or pharmacist before taking this medicine.
  • Prolonged and recurring stomach problems can be a sign of a serious illness, such as B. a stomach or duodenal ulcer. Treatment with the drug should therefore not last longer than 14 days without a medical examination. If you develop tarry stools, blood in your stools or vomit blood, consult a doctor immediately.
  • With long-term use of the drug, regular monitoring of the aluminum serum level is required. 40 µg/l should not be exceeded.
  • In patients with impaired kidney function and chronic intake of high doses, there is the possibility of poisoning such as an increase in the magnesium or aluminum level in the blood.
  • Long-term intake of high doses and a low-phosphate diet can lead to phosphate depletion with the risk of softening of the bones (osteomalacia). Long-term use of high doses should therefore be avoided in patients with impaired renal function.

• Driving and using machines:
  • There are no special features to consider.