Endofalk® Classic Powder Sachet
Macrogol-based intestinal irrigation solution, free of Glauber's salt, for intestinal cleansing in preparation for colonoscopy.
Pleasantly flavored in orange/passion fruit (Endofalk® Classic) or pineapple/lemon (Endofalk® Tropic) flavors.
Active ingredients
- 1400 mg sodium chloride
- 715 mg sodium bicarbonate
- 185 mg potassium chloride
- 52500 mg Macrogol 3350
Excipients
- Orange aroma
- Silicon dioxide, highly dispersed
- Saccharin sodium
- Passion fruit aroma
Indication :
- The medicine is a powder for preparing an oral solution with a laxative effect.
- It is used to cleanse the intestines in preparation for a colonoscopy.
Dosage :
- Always take this medicine exactly as your doctor has told you. If you are not sure, ask your doctor or pharmacist.
- For complete bowel cleansing, you must take 3 or a maximum of 4 liters of the medicine. 1 sachet corresponds to ½ liter of solution.
- Drink the solution in portions of 200 - 300 ml every 10 minutes until you notice that the discharge from the anus is clear.
- It is taken over a period of about 4 hours, usually on the day of the examination. You can also take the entire amount required the evening before, or drink part of it the evening before and the rest on the morning of the examination day.
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Duration of application
- The medicine is intended for single use before a planned bowel examination.
- Please talk to your doctor if you feel that the effect is too strong or too weak.
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If you take more of this medicine than you should
- Diarrhoea or watery stools is the goal of treatment with the drug. However, if you have taken significantly more of the medicine than you should, severe diarrhoea symptoms will occur.
- In this case, you should drink plenty of fluids and definitely ask your doctor for advice.
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If you forget to take the medicine
- If you drink significantly less than the recommended amount, your bowels may not be emptied thoroughly. The examination cannot then be carried out as planned. Therefore, please follow your doctor's dosage recommendation or the recommendation.
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If you stop treatment with the medicine
- If you interrupt or stop taking the medicine early, your bowels may not be emptied thoroughly. The examination cannot then be carried out as planned.
- If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
Manner :
- Drink the solution in portions of 200 - 300 ml every 10 minutes until you notice that the discharge from the anus is clear.
- It is taken over a period of about 4 hours, usually on the day of the examination. You can also take the entire amount required the evening before, or drink part of it the evening before and the rest on the morning of the examination day.
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Preparation of the solution
- Please prepare the solution fresh before use. The contents of one sachet are dissolved in half a liter of lukewarm water. In this way, prepare 3 - 4 liters of solution. Since 1 sachet of solution corresponds to ½ liter of solution, you will need 6 to 8 sachets to prepare 3 - 4 liters of solution. After preparation, you can put the ready-to-use solution in the refrigerator to cool down. The cooled solution is more pleasant to drink.
Side effects :
- Like all medicines, this medicine can cause side effects, although not everybody gets them.
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Important side effects or signs to look out for and what to do if you are affected
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All medicines can cause allergic reactions. However, severe allergic reactions are very rare. If you experience any of the side effects listed below, stop taking the medicine and see your doctor as soon as possible:
- Allergic rash
- Circulatory problems
- Shortness of breath
- Sweating with nausea
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All medicines can cause allergic reactions. However, severe allergic reactions are very rare. If you experience any of the side effects listed below, stop taking the medicine and see your doctor as soon as possible:
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The following side effects were also observed
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Very common: may affect more than 1 in 10 people
- Nausea, bloating and flatulence
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Common: may affect up to 1 in 10 people
- Vomiting, stomach cramps and irritation of the anus
- These symptoms are largely due to drinking a relatively large amount of liquid in a short period of time. If gastrointestinal complaints occur, use should be temporarily slowed down or stopped until the symptoms subside.
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Uncommon: may affect up to 1 in 100 people
- General malaise and insomnia
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Very rare: may affect up to 1 in 10,000 people
- Irregular or too rapid heartbeat (cardiac arrhythmia, tachycardia) and fluid accumulation in the lungs (pulmonary edema).
- Neurological symptoms that can range from mild disorientation to general seizures as a result of a disturbed electrolyte balance in the blood.
- Hives (urticaria), nasal discharge, runny nose (rhinorrhea) or acute skin inflammation (dermatitis), which are probably of an allergic nature, anaphylactic shock.
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Not known: Frequency cannot be estimated from the available data
- Dehydration, electrolyte imbalance (low blood levels of calcium, potassium and sodium).
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Notice
- Two cases have been described in the literature in which the so-called Mallory-Weiss syndrome (vomiting with subsequent bleeding due to a tear in the esophagus) occurred as a result of vomiting after taking intestinal irrigation solutions containing macrogol.
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What countermeasures should be taken in case of side effects?
- If you experience abdominal pain or other gastrointestinal complaints, you should temporarily drink the product more slowly or stop taking it until these symptoms subside. In this case, consult your doctor.
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Very common: may affect more than 1 in 10 people
- If you notice any side effects, talk to your doctor or pharmacist. This includes any side effects not listed.
Interactions :
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Taking with other medicines
- Tell your doctor or pharmacist if you are taking/using, have recently taken/used or intend to take/use any other medicines.
- Some medicines, such as anti-epileptics, may be less effective when used at the same time as this medicine.
- However, if you absolutely must take such other medicines, ask your doctor beforehand about an alternative option.
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Taking with food and drink
- You should not eat any solid food for 2 to 3 hours before drinking and until after the examination.
- You must not add any other solutions or additives to the drinking solution (especially no sugar or incompatible flavorings), as this can, among other things, lead to a change in the electrolyte composition in your blood. In addition, the breakdown of the added substances by intestinal bacteria can lead to the development of explosive gas mixtures in the intestine.
- This medicine may counteract the effect of thickeners. This should be taken into account if you need to thicken the liquid to make it safe to swallow.
Contraindications :
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The medicine must not be taken
- if you are allergic to macrogol 3350, sodium hydrogen carbonate, sodium chloride, potassium chloride, other macrogols or any of the other ingredients of this medicine.
- if you have or are suspected of having an intestinal obstruction, narrowing or perforations in the gastrointestinal tract, or are at risk of perforations in the gastrointestinal tract.
- if you suffer from gastric emptying disorders or from a severe, highly inflammatory form of colitis and the resulting severe, pathological enlargement of the colon (toxic megacolon).
- if you have an impaired swallowing or gag reflex, or suffer from general weakness.
- The preparation should not be administered to patients with impaired consciousness and patients with a tendency to swallow or inhale liquids.
- If you experience sudden abdominal pain or rectal bleeding while taking the bowel preparation, contact your doctor or seek medical attention immediately.
Pregnancy and breastfeeding :
- If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
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pregnancy
- There is no experience with the use during pregnancy.
- If you are pregnant, your doctor will carefully weigh the benefits and risks before use.
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Breastfeeding
- If necessary, you can also take the product while breastfeeding.
Patient information :
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Warnings and precautions
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Please talk to your doctor or pharmacist before taking this medicine,
- if you suffer from chronic inflammatory bowel disease. You should consult your doctor before taking it.
- if you have inflammation of the esophagus due to reflux of stomach acid (reflux esophagitis) or certain cardiac arrhythmias (SA block or sick sinus syndrome). You should only use the preparation after consulting your doctor.
- if you are an elderly or weakened patient. In this case, your salt (electrolyte) and fluid balance should be carefully monitored.
- If you have impaired kidney function, severe heart failure, liver disease or are suffering from severe dehydration, you should not use the medicine, as in these cases the safety of its use has not been sufficiently proven.
- If you experience side effects such as swelling, shortness of breath, tiredness, dehydration (symptoms include increased thirst, dry mouth and weakness) or heart problems, you should stop taking the medicine immediately and consult your doctor.
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Children
- There is insufficient experience with the use in children. The preparation should therefore not be used in children.
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Please talk to your doctor or pharmacist before taking this medicine,
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Ability to drive and use machines
- The preparation has no or negligible influence on the ability to drive and use machines.