• 13125 mg macrogol 3350
• 351 mg sodium chloride
• 179 mg sodium hydrogen carbonate
• 46 mg potassium chloride

• Sorbitol
• Acesulfame Potassium
• Lemon flavor
• Dyes

With citrus-flavored

MACROGOL compound 3350 electrolytes sachets composition
1 sachet contains as effective ingredients:
Macrogol 3350 13.125 g
sodium chloride 0.351 g
sodium bicarbonate 0.179 g
potassium chloride 0.046 g
Excipients:
sorbitol, acesulfame potassium, flavoring, coloring

action
Macrogol TAD contains Macrogol 3350 and electrolytes as active ingredients.
Due to the high water-binding capacity of Macrogol 3350 - comparable to a liquid sponge - a lot of liquid can be transported into the intestine without being absorbed by the body. This will soften solid stool and increase stool volume. This leads to the initiation of the natural bowel movement and ultimately to the elimination of stools. Macrogol 3350 is also eliminated. The addition of electrolytes (potassium and sodium salts) results in a drinking solution that compensates for a possible loss of the body's own electrolytes or water or prevents the body from becoming exposed to fluids.

Areas of application / MACROGOL compound 3350 electrolytes sachets intended use
Chronic constipation (constipation)
Notes
Please note the information with the symbol!
marked notes with particular attention.

Contraindications
You must not take Macrogol TAD if:
intestinal constriction or intestinal obstruction,
risk of intestinal rupture,
severe inflammatory bowel diseases (such as Crohn's disease, ulcerative colitis, toxic megacolon),
hypersensitivity to one of the ingredients,

precautionary measures and special information
For symptoms that indicate a shift in the fluid and electrolyte balance, such as B. accumulation of tissue fluid (edema), shortness of breath, increasing tiredness, loss of body water (dehydration), heart failure, the intake of Macrogol TAD should be stopped immediately, electrolyte measurements taken and appropriate countermeasures taken in the event of deviations.

MACROGOL compound 3350 electrolytes sachets TAD should be used with caution:
In patients at high risk of Macrogol TAD entering the airways, e.g. B. in elderly patients with Parkinson's disease or supranuclear palsy (see also section “Side effects”).
In older, poorly nourished, frail patients who are already predestined for a folic acid deficiency. A decrease in the serum folic acid level has been observed with prolonged use of macrogol.

Children
There is insufficient experience with the use of Macrogol TAD in children. Therefore, it is not recommended for use in children under 12 years of age.

Pregnancy MACROGOL compound 3350 electrolytes sachets and breast-feeding
There is no experience regarding the use during pregnancy and breast-feeding, so Macrogol TAD should only be taken after careful consideration by the doctor.

Interactions MACROGOL compound 3350 electrolytes sachets with other means
There are no clinical reports of drug interactions. However, macrogol increases the solubility of substances that are soluble in alcohol and relatively insoluble in water. Therefore, there is a theoretical possibility that the absorption of such drugs may be temporarily reduced.

Dosage instructions, MACROGOL compound 3350 electrolytes sachets type and duration of application
Unless otherwise prescribed by the doctor, the following dosage recommendations apply:
Adults, adolescents and elderly patients
In the event of constipation, dissolve the contents of a sachet 1 to 3 times a day and drink.
For long-term use, the dose can be reduced to 1 - 2 sachets per day.

Renal MACROGOL compound 3350 electrolytes sachets impairment
No dose change is required.
Macrogol TAD treatment should normally not exceed 2 weeks. However, if necessary, Macrogol TAD can be used repeatedly.
Long-term use may be necessary in the case of severe, chronic or persistent (refractory) constipation. This can also occur in diseases such as multiple sclerosis or Parkinson's disease, or it can be caused by the use of drugs that promote constipation, such as strong pain relievers (opioids) or anti-Parkinson drugs (anticholinergics).

Method MACROGOL compound 3350 electrolytes sachets of application
The contents of one sachet are dissolved in 125 ml (1/8 liter) of water and then drunk.

Notes
The drinking solution should be freshly prepared before ingestion.
The drinking solution must not be mixed with other solutions, beverages or additives so that the electrolyte concentration is not changed.

Advice in the event of application errors and overdosing
If you accidentally ingest larger amounts than the intended dose, side effects may occur to a greater extent. As a rule, these will soon subside.
In the event of severe pain, bloating or severe diarrhea, please contact your doctor!

If you forget to take a dose, do not take a double dose, but continue using the prescribed dose.

MACROGOL compound 3350 electrolytes sachets Side effects
Gastrointestinal complaints such as bloating, abdominal pain, abdominal cramps, increased intestinal noises, nausea, vomiting and slight diarrhea (especially at the beginning) can occur. Admixtures of blood in the stool, itching and pain in the anus, and fecal incontinence have also been reported. In individual cases, hypersensitivity reactions or inflammation of the pancreas can occur. After administration via a tube, cases of serious lung disease (pulmonary edema; sometimes fatal) have been observed due to the penetration of macrogol into the airways.
Please inform your doctor or pharmacist if you notice any side effects not listed in this leaflet.

Storage of MACROGOL compound 3350 electrolytes sachets Keep out of the reach of
children!
The best before date is printed on the bags and the folding box.
Please do not use Macrogol TAD after this date.
Opened or damaged bags should not be used.
Do not store above 25 ° C!
Use only once!
Consult instructions for use!