• 40 mg procaine hydrochloride

• sodium chloride
• Sodium hydroxide for pH adjustment
• Hydrochloric acid for pH adjustment
• water for injections

WHAT IS PROCAIN PHARMARISSANO AMPOULE 2% 2ML AND WHAT IS IT USED FOR?
Procaine pharmarissano ampoule 2% 2ml is a drug for local anesthesia (local anesthetic of the ester type)
Procaine pharmarissano ampoule 2% 2ml is injected into healthy skin (intracutaneously) as part of neural therapeutic application principles.

HOW TO USE PROCAIN PHARMARISSANO AMPOULE 2% 2ML?
Procain pharmarissano ampoule 2% 2ml is generally used by a doctor. Please ask your doctor if you are unsure about the application.

Procaine pharmarissano ampoule 2% 2ml is injected into the skin (intracutaneously) depending on the required nerve blockade.

Procain pharmarissano ampoule 2% 2ml should only be used by people with the appropriate knowledge to successfully carry out the respective anesthetic procedure.

Basically, with continuous use, only low-concentration solutions of procaine hydrochloride are applied.
Repeated use of this drug may result in reversible loss of efficacy due to tachyphylaxis (rapid development of tolerance to the drug).

The solution for injection is intended for single use only. The application must take place immediately after opening the ampoule. Unused residues are to be discarded.

In principle, only the smallest dose may be administered with which the desired sufficient nerve blockade is achieved. The dosage is to be made individually according to the characteristics of the individual case.

Unless otherwise prescribed by the doctor, the following dosage recommendation applies to adolescents over the age of 15 and adults of average height:
Skin wheals: Up to 0.5 ml (equivalent to 10 mg procaine hydrochloride) per wheal.

The recommended maximum dose for one-time use in tissues from which there is rapid absorption of medicinal substances is 500 mg procaine (equivalent to 25 ml Procaine pharmarissano ampoule 2% 2ml). When used in the head, neck and genital area, the recommended single-time maximum dose is 200 mg procaine (equivalent to 10 ml procaine pharmarissano ampoule 2% 2ml) within 2 hours.

Patients with certain pre-existing conditions
In patients with certain pre-existing conditions (vascular occlusions, vascular hardening and narrowing (arteriosclerosis) or nerve damage from diabetes), the dose should also be reduced by a third. In the case of impaired liver or kidney function, increased plasma levels can occur, especially with repeated use. In these cases a lower dose range is also recommended.
Please talk to your doctor if you have the impression that the effect of Procain pharmarissano ampoule 2% 2ml is too strong or too weak.

If you use more Procain pharmarissano ampoule 2% 2ml than you should.
Procaine pharmarissano ampoule 2% 2ml acts as a stimulant on the central nervous system in low damaging doses, but in the opposite way in high damaging dose ranges, ie depression of the central functions occurs. A severe overdose occurs in 2 phases:
Symptoms of an overdose are expressed in the patient becoming restless, complaining of dizziness, acoustic and visual disturbances and tingling, especially in the tongue and lip area. Speech is slurred, chills and muscle spasms herald an imminent seizure affecting the whole body. As the poisoning of the central nervous system progresses, there is increasing dysfunction of the brainstem with the symptoms of restricted breathing and coma, leading to death.

Emergency measures and antidotes will be initiated immediately by the treating doctor according to the signs of illness.

If you have any further questions on the use of the medicine, ask your doctor or pharmacist.

CONTENTS OF THE PACK AND OTHER INFORMATION
What Procain pharmarissano ampoule 2% 2ml contains:
The active substance is procaine hydrochloride.
1 ml solution for injection contains 20 mg procaine hydrochloride.
The other ingredients are:
sodium chloride, sodium hydroxide, hydrochloric acid, water for injections.