- Ibufen, children's ibuprofen. Indications for the application of suspension Ibufen are: fever various origin (including viral infections and vaccinale). The pain of various etiologies of low to moderate severity headache, sore throat.
Composition:
5 ml of suspension contains 100 mg of ibuprofen.
Action:
a non-steroidal antipyretic, analgesic and anti-inflammatory. Anti-inflammatory mechanism of action involves the inhibition of prostaglandin cyclooxygenase activity. Inhibits severe inflammation in the synthesis of glycoproteins and prevents the release of mediators of the inflammatory process. Lowers the body temperature increased by reducing the concentration of prostaglandin E 2 in the hypothalamus. After oral administration absorbed from the digestive tract in more than 80% with peak blood levels after approximately 1 h (food delayed the absorption of ibuprofen, but does not reduce its bioavailability). Over 99% bound to plasma proteins. Ibuprofen slowly passes into joint cavities, wherein the drug concentration is maintained at a relatively long time even after the concentration in the blood. It is metabolized in the liver and excreted in the urine primarily as metabolites (70-90% of the administered dose). The drug does not tend to accumulate in the body.
Indications:
Fever of different origin (eg in the course of viral infections and vaccinale). The pain of various etiologies of low to moderate severity headache, sore throat, muscle aches, joints and bones (including viral infections, injuries due to traffic organs such as the strain and sprains), postoperative pain, toothache , pain after tooth extraction pain seaming, otic pain in inflammation of the middle ear.
Contraindications:
Hypersensitivity to the components of the preparation. Hypersensitivity to aspirin or NSAIDs manifested by rhinitis, urticaria, cutaneous or bronchial asthma. Or previous disease, gastric or duodenal ulcers. The last trimester of pregnancy. Without consulting your doctor do not use in infants under 6 months of age
Pregnancy and lactation:
Do not use the third trimester of pregnancy (the drug can suppress the farrowing or cause premature atresia ductus arteriosus). In the first and second trimester of pregnancy only be used in case of absolute necessity. Ibuprofen may in small amounts into breast milk, it is not necessary withdrawal of infants from the breast.
Dosage:
Oral. The daily dose: 20-30 mg of ibuprofen / kg body weight in divided doses. Infants 6-12 months of age (7,7-9 kg): 2.5 ml 3-4 times a day (150-200 mg / day). Children from 2-4 years of age (10-15 kg): 5 ml 3 times per day (300 mg / day). Children 5-7 years of age (16-20 kg): 7.5 ml three times per day (450 mg / day). Children 8-10 years of age (21-29 kg): 10 ml 3 times per day (600 mg / day). Children 11-13 years of age (30-40 kg): 15 ml 3 times per day (900 mg / day). The product can also be used (only on the order of a physician) in the course vaccinale in infants 3-6 months of age (5-7,6 kg) 2.5 ml of 2 times a day (to give a second dose after 6 h).