BAMBUSA D 1 globules 10 g Bambusa arundinacea

DHU-Arzneimittel GmbH & Co. KG

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BAMBUSA D 1 globules

Active ingredient: Bambusa arundinacea (homeoph.)

Vamsha – Bambusa arundinacea is a plant mentioned in Ayurveda for the treatment of cough, skin diseases, wounds, digestive disorders, nausea, gynecological disorders and fever.

Bambusa arundinacea family Graminae is highly reputed ayurvedic medicinal tree commonly known as the Bamboo. It is tall sized tree growing throughout India, moist parts of India. It also occurs in Sri Lanka, Malaya, Peru and Myanmar. The different parts of this plant contain silica, Cholin, betain, cynogenetic glycosides, albuminoids, Oxalic acid, reducing sugar, resins, waxes, benzoic acid, Arginine, cysteine, histidine, niacin, riboflavin, thiamine, Protein, gluteline, contains lysine, methionine, betain, cholin, proteolytic enzyme, nuclease, urease. Various parts of this plant such as Leaf, root, shoot and seed possess Anti-inflammatory, Antiulcer, Anti-diabetic, Anti-oxidant, anthelmintic, astringent, emmengogue activity. Various phytopharmacological evaluations have been reported in this literature for the important potential of the Bambusa arundinacea.

Antidiabetic activity Aqueous ethanolic solvent extracts of Bambusa arundinacea seeda werw tested for anti-diabetic activity using alloxan indused diabetic rats and compared with standard. The result expressed that aqueous ethanolic extracts had shown significant protection and maximum reduction in blood glucose was observed in alloxan indused diabetic rats.

The results of this comprehensive study reveal that Bambusa arundinacea seed shown statistically significant Anti-Diabetic activity in comparision to the standard glibenclamide (Macharla, 2011). Antifertility effect An ethanolic extract of Bambusa arundinacea tender shoots (BASE) caused a reduction in fertility of male rats. After administration of 300 mg/kg per day of BASE for 7 days, the fertility index decreased to 15% for control rats and to 23% after a 7day recovery period, respectively. The number of cohabited females being successfully inseminated was reduced especially after 4 days of treatment. Complete recovery of mating behavior was evident 8 days after BASE withdrawal. The number of spermatozoa in the caput and cauda epididymis were decreased concomitant with a decrease in the motility of spermatozoa collected from the cauda epididymis.

The weights of testes, epididymides, vas deferens and prostate were also significantly decreased. The serum profile of protein and oxaloacetic/pyruvic transaminase activity show the extract to be relatively non-toxic (Vanithakumari et al., 1989). Antibacterial activity Water-phase extract of bamboo shavings (WEBS), by supercritical carbon dioxide extraction, was evaluated for its antimicrobial action against the range of food borne and food spoilage pathogens using agar disc diffusion assay in nutrient agar and Czapek Dox Agar media. The WEBS exhibited antimicrobial activity against Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Aspergillus niger, Penicilliun citrinum and Saccharomyces cerevisiae with a concentration-dependent relationship.

The minimum inhibitory concentrations (MICs) of the WEBS against the tested bacterial strains were found in the range of 4.9 - 32 mg/ml using the two-fold dilution method. Different heat treatment conditions have no significant influence on the antibacterial activity. Emodin was taken as the standard sample to test for the content of total anthraquinone compound and preliminarily verify its antibacterial mechanism, so as to lay a theoretical foundation for development of its natural preservatives (Zang et al., 2010).

Antiinflammatory and Antiulcer The extracts of Bambusa arundinacea have been used in Indian folk medicine to treat various inflammatory conditions. The plant has got antiulcer activity also. It is thought that these two properties in the same extract are very much useful in the treatment of inflammatory conditions. It is well known fact that the most of the available antiinflammatory drugs are ulcerogenic. The antiinflammatory effect of the methanol extract of the leaves of Bambusa arundinacea against carrageenin-induced as well as immunologically induced paw oedema and also its antiulcer activity in albino rats have been studied and found to be significant when compared to the standard drugs.

The combination of methanol extract and phenylbutazone (Non-Steroidal Antiinflammatory Agent, NSAIA) has been studied and found to be the most potent antiinflammatory activity experimentally with least toxic (no ulcerogenic) activity. Thus, the combination of herbal product (methanol extract of Bambusa arundinacea) with modern medicine (NSAIAs) will produce the best antiinflammatory drug and will be useful for long-term treatment of chronic inflammatory conditions like rheumatoid arthritis with peptic ulcer, which are common (Muniappan et al., 2003).

Protective effects Two biological activities of bamboo-derived pyrolyzates were investigated; the protective effects against N-methyl-daspartate (NMDA)-induced cell death in primary cultured cortical neuron and the anti-plasmin effects determined by using fibrin and fibrinogen degradation products (FDPs) assay.

Results: Treatment of neuronal cells with pyrolyzates of Phyllostachys pubescens, Phyllostachys nigra and Phyllostachys bambusoides resulted in restored cell viability when compared to untreated cells in an NMDA-induced neuronal cell death assay. In addition, cortical neurons treated with Phyllostachys pubescens and Phyllostachys nigra showed a reduction of apoptosis following exposure to NMDA, as determined by Hoechst 33342 staining. In addition,

Phyllostachys nigra pyrolyzates also exhibited anti-plasmin action in a FDP assay. It is of interest to note that pyrolyzates exhibited activities of NMDA-receptor antagonist and antifebrin (ogen), since a combination of NMDA receptor antagonists, glucocorticosteroids, GABAergic drugs and heparin are useful for