The active substance used in Depremin is the dry extract of St. John's wort (612 mg in each tablet). This preparation is a herbal medicine for use in the short-term treatment of the symptoms of mild depressive disorder.
Composition of Depremin:
Active substance: dry extract of St. John's wort (Hyperici herbae extractum siccum quantificatum). One film-coated tablet contains 612 mg of extract (in the form of a dry, quantified extract) from Hypericum perforatum L., herba (St. John's wort) (DER primary 3-6: 1), which corresponds to: 0.6-1.8 mg of the sum of hypericins in terms of hypericin, 36.72-91.80 mg of the sum of flavonoids in terms of routine, no more than 36.72 mg of hyperforin. Extraction solvent: ethanol 60% (V / V). The excipients are: colloidal anhydrous silica, microcrystalline cellulose, croscarmellose sodium, colloidal anhydrous silica, magnesium stearate, coating mixture Opadry II 85F32410 yellow (polyvinyl alcohol, titanium dioxide, macrogol 3350, talc, iron oxide yellow (E 172)).
The indications for the use of the herbal medicinal product Depremin are symptoms associated with mild depressive disorders. The composition of the drug contains dry extract of St. John's wort - 612 mg of the active substance in each tablet. The drug should be used for a short time. If your symptoms do not improve or worsen after 4 weeks of treatment, you should seek medical advice.
The medicinal product Depremin indicated for the short-term treatment of the symptoms of mild depressive disorders.
Store the product out of reach of children at room temperature. It is recommended to protect against the effects of moisture and light. St. John's wort may affect the action of some medications (e.g. oral contraceptives), therefore people taking any medications should consult their doctor before taking Depremin. It is usually advisable to stop treatment before elective surgery as there is a risk of interactions with anesthetic agents. In the case of simultaneous use of St. John's wort and antidepressants (serotonin reuptake inhibitors, triptans, buspirone), serotonergic effects may be increased (e.g. nausea, vomiting, agitation, confusion, anxiety). It is recommended to avoid exposure to intense ultraviolet radiation during treatment.
Do not use in case of hypersensitivity to any component of the drug. Do not use in combination with drugs that reduce the transplant rejection reaction (cyclosporine, tacrolimus for systemic use), drugs used to treat HIV infection (amprenavir, indinavir and other protease inhibitors), anticancer drugs (irinotecan) and anticoagulants (warfarin).
Some people may experience side effects during treatment. Not known: gastrointestinal disorders, allergic skin reactions, fatigue and anxiety. People with fair skin may experience severe sunburn-like symptoms in the presence of intense sunlight.
Dosage of Depremin tablets:
Use as directed by your doctor or according to the instructions on the leaflet. The recommended daily dose for adults is one tablet (612 mg). Use orally, drink with liquid. The usual duration of treatment is 6 weeks, with a therapeutic effect expected within the first four weeks of use. If symptoms persist after a month of treatment, consult your doctor.