DONA 1500 mg knee osteoarthritis relief

MEDA Pharma GmbH & Co.KG

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Dona® 1500 mg sachet knee osteoarthritis relief
powder for oral solution

Active substance:
glucosamine hemisulphate.
One sachet contains: 1884 mg glucosamine hemisulphate sodium chloride (1: 1), equivalent to 1500 mg glucosamine hemisulphate or 1178 mg glucosamine.

Areas of application:
For the relief of symptoms of mild to moderate osteoarthritis of the knee joint.

Knee osteoarthritis relief  Active ingredients

  • 1884.14 mg D-glucosamine hemisulfate sodium chloride from shellfish

Knee osteoarthritis relief  Auxiliary materials

  • 151 mg sodium ion
  • 2.5 mg aspartame
  • 2028.5 mg sorbitol
  • Citric acid
  • Macrogol 4000

Knee osteoarthritis relief  Indication / application

  • The preparation belongs to a group of medicines called other nonsteroidal anti-inflammatory (anti-inflammatory) and anti-rheumatic (anti-inflammatory) medicines.
  • It is used to relieve symptoms of mild to moderate osteoarthritis of the knee joint.

Knee osteoarthritis relief dosage

  • Always take the medicine exactly as instructed in the package leaflet. Please ask your doctor or pharmacist if you are not sure.
  • Unless otherwise prescribed by your doctor, the usual dose is:
    • 1 sachet per day.
  • Glucosamine is not indicated for the treatment of acute painful symptoms as symptom relief (especially pain relief) does not occur until a few weeks after starting treatment, and in some cases later.
  • If symptom relief is not seen after 2-3 months, continued glucosamine treatment should be reviewed.


  • If you take more than you should
    • If you take more medicine than you should, you must contact your doctor or a hospital.


  • If you forget to take a dose
    • Do not take a double dose to make up for a forgotten dose


  • If you stop taking it
    • Your symptoms may come back.


  • If you have any further questions on the use of the medicinal product, ask your doctor or pharmacist.

Knee osteoarthritis relief way

  • Take the contents of one sachet dissolved in a glass of water, preferably with a meal.

Side effects

  • Like all medicines, the preparation can cause side effects, although not everybody gets them. The frequency of side effects is based on the following categories:
    • Very common: affects more than 1 in 10 people
    • Common: affects 1 to 10 users in 100
    • Uncommon: affects 1 to 10 users in 1,000
    • Rare: affects 1 to 10 users in 10,000
    • Very rare: less than 1 user in 10,000
    • Not known: frequency cannot be estimated from the available data
  • The following side effects have been reported:
    • Frequently:
      • Headache, fatigue, drowsiness, nausea, abdominal pain, indigestion, gas, diarrhea, constipation
    • Occasionally:
      • Eczema, itching, reddening of the skin
    • Not known:
      • Allergic reaction, dizziness
    • Isolated, spontaneous cases of elevated cholesterol levels have been reported, but a causal relationship has not been established.
  • Tell your doctor or pharmacist if you get serious about any of the side effects listed, or if you notice any side effects that are not listed.

Knee osteoarthritis relief Interactions

  • When taking the preparation with other drugs
    • Please tell your doctor or pharmacist if you are using or have recently used any other medicines, including medicines obtained without a prescription.
    • Caution should be exercised when the preparation is used in conjunction with other medicinal products, especially warfarin and tetracyclines. Ask your doctor for advice.
  • When taking the preparation with food and drink
    • It is recommended to take the contents of one sachet, ideally with a meal, dissolved in a glass of water.


  • Do not take the medicine
    • if you are hypersensitive (allergic) to glucosamine or any of the other ingredients.
    • if you are allergic (hypersensitive) to shellfish, as glucosamine is made from shellfish.

Knee osteoarthritis relief pregnancy and breast feeding period

  • Ask your doctor or pharmacist for advice before taking this medicine if you are pregnant or breast-feeding, if you suspect you may be pregnant or planning to become pregnant.
  • pregnancy
    • The preparation should not be used during pregnancy.
    • There are no data on the safety of use in pregnant women. If you are pregnant, you should therefore only use the medicine if your treating doctor considers it absolutely necessary. If you are planning a pregnancy or are already pregnant, please contact your doctor immediately so that he or she can decide whether to continue or discontinue the treatment.
  • Breastfeeding
    • The use of glucosamine while breastfeeding is not recommended.

Knee osteoarthritis relief Patient information

  • Take special care when taking the drug
    • if you suffer from impaired glucose tolerance. More frequent blood glucose measurements may be needed when starting glucosamine treatment.
    • if you suffer from impaired liver or kidney function, as no studies have been carried out in this group of patients, no dose recommendations can be made.
    • if you are known to be at increased risk of cardiovascular disease, as in some cases an increase in lipid levels has been seen in patients treated with glucosamine.
    • if you have asthma. When you start taking glucosamine, be prepared for any possible worsening of symptoms.
  • Children and adolescents
    • Due to the lack of data on its safety and efficacy, the preparation is not recommended for use in children and adolescents under 18 years of age.
  • Elderly people
    • No specific studies have been conducted in the elderly, but based on clinical experience, no dose adjustment is required when treating otherwise healthy elderly people.
  • Impaired liver or kidney function
    • No studies have been performed in patients with impaired liver or kidney function. No dosage recommendations can therefore be made for these patients.


  • Driving and using machines
    • No studies on the effects on the ability to drive or use machines have been performed. If you are dizzy or light-headed, it is recommended that you refrain from driving or operating machines.