Active substance: 15 ml of Duphalac contains the active ingredient: 10 g lactulose and <1.65 g galactose <0.9 g of lactose, and trace quantities of other sugars.
Duphalac, the laxative drug, osmotic used to treat chronic constipation and recurrent hepatic encephalopathy, and - the prevention and treatment of hepatic coma. Operation of the drug is also affected by dilution of stool consistency, and therefore is not recommended for use in patients after surgery and surgery of the colon or rectum to facilitate defecation. In the large intestine, lactulose is degraded by intestinal bacteria into low-molecular organic acids, such as lactic acid and acetic acid. This leads to acidify the intestinal contents, which stimulates the motility of the (contraction), and changes in osmotic pressure (download water into the intestinal lumen), which normalizes the stool consistency.
The drug should be used as prescribed. The drug is taken orally.
Daily doses should be individualized. The information below is indicative.
Oral. In hepatic coma and in states initially 3 times a day for 30-50 ml. After a few days, the dose should be reduced and adapted to the individual needs of the patient. In chronic constipation initial dose: adults 30 ml per day; children 7-14 years of age 5 ml per day, children 2-6 years of age 10 ml per day, infants 5 ml per day. After a few days of the dose should be reduced and adapted to the individual needs of the patient. The maintenance dose should be determined so that the patient indulged 2-3 loose stools a day, stool pH should be 5.0-5.5. The preparation may be administered alone or mixed with food.
Hypersensitivity to the components of the preparation. Bowel obstruction, sudden abdominal pain, galactosemia.