• 5 mg folic acid

• magnesium stearate
• Silica, colloidal
• cellulose powder
• lactose-1 water
• talc

indication Folic acid, folic acid deficiency, DREISAFOL tablets

• The drug is a vitamin.
• The drug is used in folic acid deficiency conditions that cannot be corrected with diet.

dosage Folic acid, folic acid deficiency, DREISAFOL tablets

• Always take the medicine exactly as your doctor has told you.
• Please check with your doctor or pharmacist if you are not sure.
  • Unless otherwise prescribed by the doctor, is the usual dose
    • Depending on requirements, 1 to 3 tablets per day (equivalent to 5 - 15 mg folic acid).
    • During pregnancy, the maximum daily dose is 5 mg.

• duration of use
  • The duration of treatment depends on the extent of the folic acid deficiency and depends on the clinical picture and, if necessary, on the corresponding laboratory diagnostic parameters and is determined by the doctor for each patient.
  • Doses higher than 5 mg daily should be avoided during pregnancy.

• If you take more of the medicine than you should
  • No signs of overdose are to be expected with occasional higher dosages.
  • In patients with seizure disorders, however, there may be an increase in the likelihood of seizures.
  • At high doses (above 15 mg per day and longer than 4 weeks), gastrointestinal disorders, sleep disorders, agitation or depression can occur. In these cases you should contact your doctor.

• If you have any further questions on the use of the medicine, ask your doctor or pharmacist.

way

• The tablets are swallowed whole with a meal with some liquid.

side effects

• Like all medicines, this can cause side effects, although not everyone gets them.
  • The evaluation of side effects is based on the following frequency information:
    • very common: more than 1 in 10 people treated
    • Common: less than 1 in 10 but more than 1 in 100 people treated
    • uncommon: less than 1 in 100 but more than 1 in 1000 people treated
    • rare: less than 1 in 1,000 but more than 1 in 10,000 people treated
    • very rare: 1 or less in 10,000 people treated including isolated cases
  • In individual cases, intolerance reactions, e.g. B. in the form of reddening of the skin (erythema), itching (pruritus), shortness of breath (bronchospasm), nausea or circulatory collapse (anaphylactic shock).
  • Very high doses can lead to gastrointestinal disorders, sleep disorders, excitement or depression.
  • Please tell your doctor or pharmacist if any of the side effects gets serious, or if you notice any side effects not listed here.

interactions

• Taking the medicine with other medicines
  • Please tell your doctor or pharmacist if you are using or have recently used any other medicines, including medicines obtained without a prescription.
  • The administration of folic acid can lower the blood levels of antiseizure drugs (anticonvulsants, e.g. phenytoin, phenobarbital, primidone) and thereby possibly increase the likelihood of seizures.
  • When high doses are administered, it cannot be ruled out that the medicinal product and simultaneously administered folic acid inhibitors (folic acid antagonists), e.g. B. certain drugs against bacterial infections or malaria (trimethoprim, proguanil, pyrimethamine) and methotrexate (active ingredient for the treatment of tumors, among other things) mutually inhibit their effect.
  • Severe diarrhea can occur if used at the same time as fluorouracil (medicine used to treat tumours).
  • Chloramphenicol (active substance used to treat infections) can prevent the response to treatment with the medicine and should therefore not be given to patients with severe folic acid deficiency.

Contraindications

• The drug must not be taken
  • if you are allergic (hypersensitive) to folic acid or any of the other ingredients of the medicine.
  • The increase in young red blood cells (reticulocytes) caused by folic acid can mask vitamin B12 deficiency. Because of the risk of irreversible neurological disorders, before treating anemia due to impaired development of the red blood cells (megaloblastic anemia), it must be ensured that this is not due to a vitamin B12 deficiency. The cause of megaloblastic anemia must be clarified before starting therapy.

pregnancy and breast feeding period

• pregnancy and breast feeding period
  • There are no known risks up to a daily dose of 5 mg.
  • There is not enough experience with the use of a daily dose of more than 5 mg folic acid during pregnancy, so the maximum daily dose of 5 mg folic acid should not be exceeded.
  • Ask your doctor or pharmacist for advice before taking any medicine.

patient notes

• Special care is required when taking the drug
  • Even in the case of life-threatening megaloblastic anemia, a possible vitamin B12 deficiency must be ruled out before the start of therapy (serum and erythrocyte samples and determination of the vitamin B12 content) due to the risk of permanent damage to the nervous system.
  • There is not enough experience with the use of a daily dose of more than 5 mg folic acid during pregnancy, so the maximum daily dose of 5 mg folic acid should not be exceeded.