- FOSIDAL syrup formulation containing an active substance fenspiride hydrochloride salt used to treat the symptoms of cough and sputum in the course of inflammatory diseases of the lungs and bronchi.
Composition:
The active substance is fenspiride hydrochloride. 1 ml of syrup contains 2 mg of fenspiride hydrochloride.
The other ingredients are:
methyl parahydroxybenzoate (E 218) propyl parahydroxybenzoate (E 216), potassium sorbate (E 202), glycerol, saccharin sodium (E 945), sucrose, vanilla aroma, honey aroma, sunset yellow (E 110) citric acid monohydrate, purified water.
Indications:
- Symptomatic treatment of cough and sputum during inflammatory diseases of the lungs and bronchi
Action:
The preparation Fosidal anti-inflammatory and bronchodilator relaxant. The medicament contains the active substance fenspiride hydrochloride, which antagonizing the histamine H, and also has a spasmolytic effect type papawerynowego. Anti-inflammatory effect by reducing the production of mediators of inflammation (cytokines, TNF-α, arachidonic acid derivatives, free radical). After oral administration of the drug reaches maximum concentration in the plasma. After about 2.5 h. The half life is 12 hours, and excretion occurs mainly via the kidneys.
Contraindications:
- Hypersensitivity to the active substance fenspiride hydrochloride or any of the excipients Fosidal
- alcohol
- do not use in children less than 2 years
Dosage Fosidal:
preparation Fosidal administered orally, immediately before a meal. Adult is administered from 45 ml to 90 ml per day. Children older than 2 years: 4 mg / kg per day (children weighing less than 10 kg: 10 ml and 20 ml of syrup per day in divided doses, and children weighing more than 10 kg: 30 ml 60 ml of the syrup daily in divided doses).