LIVOSIL. Silybum marianum. Use of adult toxic liver lesions.
LIVOSIL 140 mg hard capsules
Silymarin
Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.
Always take this medicine exactly as described in this leaflet or as directed by your doctor or pharmacist.
- Keep this leaflet You may need to read it.
- If you want more information or advice, ask your pharmacist.
- If you get side effects (even if it is not listed), ask your doctor or pharmacist. See. Chapter 4.
- If your well-being has not improved or even worse, see your doctor.
What is in this leaflet?
- What is LIVOSIL is and what it is used for
- Before you LIVOSIL
- How LIVOSIL
- Possible side effects
- How to store LIVOSIL
- Contents of the pack and other information
- What is LIVOSIL is and what it is used for
LIVOSIL active substance is true Milk Thistle (Silybum marianum) derived from the seeds of vegetable active ingredient silymarin. Silymarin has a protective effect on the liver. Research suggests that silymarin caused a strong antioxidant and glutathione concentration of intracellular regulating effect and binds free radicals, slows down the liver of harmful substances into the liver cells, promote liver regeneration, and inhibit the accumulation of collagen fibers in the liver. Such disorders occur during liver cirrhosis.
LIVOSIL hard capsules, as an additional tool to be used in adults to treat toxic liver injury. Also, the product may be used in combination with other drugs for chronic hepatitis and liver cirrhosis treatment.
If your well-being has not improved or even worse, see your doctor.
- Before you LIVOSIL
LIVOSIL Do not
If you are allergic (hypersensitive) to silymarin or any of the other ingredients LIVOSIL material (
listed in Section 6).
Warnings and Precautions
Check with your doctor or pharmacist before taking LIVOSIL.
If you have diabetes or impaired glucose concentration in the blood or taking medicines, food
supplements or other products that affect blood glucose levels. LIVOSIL can reduce glucose
concentration in the blood.
Other medicines and LIVOSIL
If you are taking or have recently taken any other medicines, or because you are not sure, talk to your doctor or pharmacist.
Not that LIVOSIL interact with other medicines.
LIVOSIL with food and drink
LIVOSIL can be taken with or without food.
Pregnancy and breast-feeding
If you are pregnant or breast-feeding, you think that maybe you are pregnant or planning to become pregnant before taking this medicine, talk to your doctor or pharmacist.
Animal studies indicate direct or indirect harmful effects on pregnancy, embryonic or fetal development, parturition or postnatal. Studies in pregnant women and nursing mothers should not, therefore, during those periods, the medicine is not recommended.
Driving and using machines
LIVOSIL ability to drive and use machines.
- How LIVOSIL
Always take this medicine exactly as directed by your doctor or pharmacist. If in doubt, ask your doctor or pharmacist.
The usual dose for adults is LIVOSIL 280¬ - 420 mg per day. You can take one 140 mg hard capsule twice a day or one 140 mg hard capsule three times a day.
The product is recommended for more than 3 months.
Elderly patients with renal impairment, dose adjustment is required.
Use in children and adolescents
LIVOSIL is not recommended for use in children and adolescents under 18 years of age.
If you take a large dose LIVOSIL
If you take too high a dose, contact your doctor or the nearest hospital emergency department.
If you forget to LIVOSIL
If you forget to take a dose, take it as soon as prisimisite. If it is almost time for your next dose, skip the missed dose and take the medicine procedures. Do not take a double dose to make up for a missed dose.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
- Possible side effects
LIVOSIL, like all medicines, can cause side effects, although not everybody gets them.
LIVOSIL may experience the following side effects:
disorders, which (can not be estimated from the available data): headache, dizziness, abdominal discomfort, diarrhea, itching and hives.
If the side effects gets serious, or if you notice any side effects not listed, please tell your doctor or pharmacist.
Reports of side effects
If you experience side effects, including not listed, please tell your doctor or pharmacist. The side effects can also report directly by filling out the web site www.vvkt.lt
the form by mail to the State Medicines Control Agency under the Lithuanian Ministry of Health, Žirmūnų g. 139A, LT 09120 Vilnius Tel: 8 800 73 568, fax 8 800 20131 or e-mail. Email NepageidaujamaR@vvkt.lt notifying side effects can help us to get more information about the safety of the medicine.
- How to store LIVOSIL
Keep this medicine out of the sight and reach of children place.
Do not store above 25 o C.
On the carton and blister after EXP after the expiry date of this medicine. The expiry date refers to the last day of the month.
Medicines should not be disposed of via wastewater or household waste. How to dispose of medicines no longer required, ask your pharmacist. These measures will help to protect the environment.
- Contents of the pack and other information
LIVOSIL composition
- The active substance is silymarin. Each capsule contains 215.38 - 350 mg and Silybum marianum (L.) Gaertn., Fructus (milk thistle fruit) refined and standardized dry extract (24-27: 1), corresponding to 140 mg of silymarin, calculated in accordance with sylibanin.
Extraction solvent: acetone: water (95: 5).
or
Each capsule contains 215.38 - 350 mg and Silybum marianum (L.) Gaertn., Fructus (milk thistle fruit) refined and standardized dry extract (36-44: 1), corresponding to 140 mg of silymarin, calculated in accordance with sylibanin.
Extraction solvent: ethyl acetate.
- Excipients: anhydrous calcium hydrogen phosphate, sodium salt, talc, magnesium stearate, colloidal anhydrous silica, the capsule housing - gelatin, titanium dioxide (E171), red iron oxide (E172).
LIVOSIL appearance and contents of the pack
LIVOSIL hard capsules are brown, cylindrical, filled with yellow powder.
LIVOSIL packaged in blister packs of 15 capsules. Blister packages are packed in a cardboard box containing 15, 30, 45 or 60 capsules.
It may not be available in all packs.