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Macrogol 3350 sachets, MACROGOL ADGC plus Electrolytes

Zentiva Pharma GmbH

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MACROGOL ADGC plus Electrolytes, Macrogol 3350 sachets

Dosage form:Powder for oral solution

MACROGOL ADGC plus electrolytes
powder for oral solution

Active ingredients:
Macrogol 3350, sodium chloride, sodium hydrogen carbonate, potassium chloride.

Areas of application:
For the treatment of constipation in adults and adolescents over 12 years of age.

Warning: contains 190 mg sodium per sachet.


For information about risks and side effects, read the package leaflet and ask your doctor or pharmacy.
‍ Pharmaceutical entrepreneur: Zentiva Pharma GmbH, 65927 Frankfurt am Main.‍

The stomach is tense and pressing. You feel a strong feeling of fullness but still can't go to the toilet: constipation is one of the most common complaints in Germany - and quite unpleasant. In Europe, it is estimated that around 15 percent of people feel this way. Women are affected more often than men, older people more than younger people. If constipation - this is the medical term for constipation - is accompanied by abdominal discomfort and pain, this can indicate irritable bowel syndrome.

Medication can help effectively. That's why more than three million people take medication to combat constipation. A lot has happened here in recent years; thanks to advanced medical research, the drugs are extremely effective and very low-risk. The active ingredient Macrogol 3350 is very effective against constipation and has almost no side effects.

ADGC, - If you don't ask, you pay more.
We at ADGC believe that health must be affordable for everyone. That's why we have specialized in the production of generics. These are drugs that are in no way inferior in quality to the original preparations, but cost much less. This way you can save a lot. But not your health!

The active ingredient macrogol is one of the drugs of first choice in the treatment of constipation. The drug MACROGOL ADGC ® plus electrolytes with the active ingredient macrogol 3350 has a laxative effect - gentle and effective. International and national medical guidelines explain the positive effect: The powder, which is dissolved in water, increases the frequency of bowel movements and improves the consistency of the stool. It provides such reliable relief.

MACROGOL ADGC ® plus electrolytes
• Effective and well-tolerated help with constipation
• Pleasant lemon taste
• No habituation effect
• Lactose-free
• For adults and young people aged 12 and over

The most frequently asked questions and answers about MACROGOL ADGC ® plus electrolytes

What is MACROGOL ADGC ® plus electrolytes and what is it used for?
MACROGOL ADGC ® plus electrolytes is a white, crystalline powder that can be dissolved in water. The solution can be taken for constipation as it softens the solid, lumpy stool and stimulates the intestines to expel the stool.

What kind of active ingredient is macrogol?
The active ingredient Macrogol 3350 has a laxative effect because the active ingredient attracts water and thus increases the volume of the stool. This makes the chair softer and more slippery. The activity of the intestines is stimulated and the softened stool is transported to the anus. It can also be excreted more easily. The electrolytes contained in MACROGOL ADGC ® plus electrolytes are exchanged via the intestinal mucosa with serum electrolytes - charged ions of salts dissolved in blood serum - and excreted together with the absorbed water. Although the body loses a small amount of water, the nutritional content of sodium, potassium and water remains the same.

The active ingredient macrogol 3350, which is contained in the medicine MACROGOL ADGC ® plus electrolytes, passes through the intestine unchanged. It is almost not absorbed in the gastrointestinal tract. The small amount that is absorbed is excreted in the urine.

What ingredients does MACROGOL ADGC ® plus electrolytes contain?
Each sachet of MACROGOL ADGC ® plus electrolytes powder contains the following active ingredients:
• Macrogol 3350 13.125 g
• Sodium chloride 350.7 mg
• Sodium bicarbonate 178.5 mg
• Potassium chloride 46.6 mg

If the powder is dissolved in 125 ml of water, the solution contains the following amounts of electrolytes:
• Sodium ion 65 mmol/L
• Potassium ion 5.4 mmol/L
• Chloride 53 mmol/L
• Bicarbonate ion 17 mmol/L

How is MACROGOL ADGC ® plus electrolytes used? Dissolve
each sachet of MACROGOL ADGC ® plus electrolytes in 125 ml of water in a glass. Stir the powder in the water with a spoon until it has dissolved. Adults and adolescents should not take more than 3 sachets daily in single doses. For long-term use as directed by your doctor, the dose can be reduced to 1 or 2 sachets daily.

Patients with kidney failure can take the same dose as other adults to treat constipation.

How long is MACROGOL ADGC ® plus electrolytes used?
Treating constipation with MACROGOL ADGC® plus electrolytes should generally not last longer than two weeks. As with all laxatives, prolonged use is not recommended. In consultation with your doctor, long-term use may sometimes be necessary if, for example, you suffer from severe chronic or persistent constipation - the medical term for constipation. This can be the case with diseases such as multiple sclerosis or Parkinson's disease, or if you have to take medications such as opioids and anticholinergics that promote constipation.

Who is MACROGOL ADGC ® plus electrolytes suitable for? MACROGOL ADGC ®
plus electrolytes powder is suitable for the treatment of constipation in adults and adolescents over 12 years of age. It has no effect on the ability to drive or use machines. MACROGOL ADGC ® plus electrolytes can be taken during pregnancy and breastfeeding, as studies have shown no influence on the unborn child and breast milk. Children under 12 years of age should not take MACROGOL ADGC ® plus electrolytes - there is a separate medicine for them on the market. Children's Macrogol 6.86 g powder for oral solution. Anyone who suffers from intestinal perforation or intestinal obstruction due to a disorder of the intestinal wall (medical term: ileus), severe inflammatory bowel disease such as Crohn's disease, ulcerative colitis and toxic megacolon should not take the powder. People who are hypersensitive to the active ingredient or ingredients must also not take MACROGOL ADGC ® plus electrolytes. What side effects does MACROGOL ADGC ® plus electrolytes have? Side effects when taking MACROGOL ADGC ® plus electrolytes are so rare that their frequency cannot be estimated because there is not enough data. In a few cases , mild intolerances such as abdominal pain, headaches, diarrhea, vomiting, nausea, flatulence or discomfort in the anal area occurred after taking MACROGOL ADGC ® plus electrolytes. appear. Very rarely, allergic reactions such as a skin rash, hives, anaphylaxis or skin swelling have occurred. In case of symptoms that indicate a shift in fluid and electrolyte balance (e.g. edema, shortness of breath, increasing fatigue, dehydration, heart failure), MACROGOL ADGC ® should be stopped

plus electrolytes should be stopped immediately. Electrolyte measurements should be carried out by a doctor and appropriate countermeasures should be taken if there are deviations.

If patients get diarrhea after taking the medication, caution is advised - especially if they are at higher risk of water-electrolyte balance disorders (e.g. older people, patients with impaired liver or kidney function or people taking diuretics).
It may also happen that the absorption of other medicines is temporarily reduced.
Further information about side effects can be found in the instructions for use.

How should MACROGOL ADGC ® plus electrolytes be stored?
The medicine can be stored in the apartment at room temperature. An already mixed solution can be stored covered in the refrigerator at 2 to 8 degrees Celsius for 24 hours.

How long does MACROGOL ADGC ® plus electrolytes last?
An unopened package of MACROGOL ADGC ® plus electrolytes has a shelf life of four years. If the powder has already been mixed with water, it will last for another 24 hours - if it is covered and stored in the refrigerator.

Macrogol 3350 sachets, MACROGOL ADGC plus Electrolytes