• 2.77 mg naratriptan hydrochloride

• 200.92 mg lactose
• cellulose, microcrystalline
• Croscarmellose sodium
• Magnesium stearate (vegetable)
• hypromellose
• titanium dioxide
• triacetin
• Iron(III) oxide hydrate, black
• Indigodisulfonic acid, aluminum salt

Naratriptan hydrochloride neuraxpharm® 2.5 mg, For use in migraines indication

• The film-coated tablets contain naratriptan (as hydrochloride), which belongs to a group of drugs called triptans (also known as 5-HT ₁ receptor agonists).
• Naratriptan film-coated tablets are used to treat migraines.
• Migraine symptoms can be caused by a temporary widening of the blood vessels in the head. It is believed that the film-coated tablets reduce this widening of the blood vessels. This will help the headache go away and relieve other symptoms of the migraine, such as: B. a general feeling of illness (nausea or vomiting) and light and noise sensitivity.

Naratriptan hydrochloride neuraxpharm® 2.5 mg, For use in migraines dosage

• Do not take the medicine until the migraine headache has started.
• Do not take it to prevent a migraine attack.
• Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.
• What amount should you take?
  • The usual dose for adults aged 18 to 65 is one film-coated tablet swallowed whole with water.
  • Naratriptan is not recommended for children under the age of 18 or adults over the age of 65.
• When should you take Naratriptan?
  • It is best to take a film-coated tablet as soon as you notice the migraine headache starting;
  • however, it can be taken at any later time during a migraine attack.
• If your symptoms return
  • You can take a second film-coated tablet after 4 hours unless you have kidney or liver disease.
  • If you have kidney or liver disease, do not take more than one film-coated tablet in 24 hours.
  • No patient should take more than two film-coated tablets in any 24-hour period.
• If the first film-coated tablet has no effect
  • Do not take another film-coated tablet for the same migraine attack.
  • If Naratriptan does not give you any relief:
    • Ask your doctor or pharmacist for advice.

• If you take more than you should
  • Do not take more than two film-coated tablets in a 24-hour period.
  • Taking too much naratriptan can make you ill. If you have taken more than two film-coated tablets within 24 hours:
    • Ask your doctor for advice.

• If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

Naratriptan hydrochloride neuraxpharm® 2.5 mg, For use in migraines way

• The usual dose for adults aged 18 to 65 is one film-coated tablet swallowed whole with water.

side effects

• Like all medicines, this medicine can cause side effects, although not everybody gets them.
• Allergic reactions: seek medical advice immediately (may affect up to 1 in 1,000 people)
  • Signs of an allergy may include: skin rash; wheezing noises; swollen eyelids, face, or lips; circulatory collapse.
  • If you notice any of these symptoms shortly after taking it:
    • Stop taking the medicine.
    • See a doctor immediately.
• Common side effects (may affect up to 1 in 10 people)
  • Nausea and vomiting, which can also be triggered by the migraine attack itself
  • Tiredness, drowsiness or a general feeling of being unwell
  • Dizziness, tingling sensation, hot flashes
  • If you notice any of these symptoms:
    • Inform your doctor or pharmacist.
• Uncommon side effects (may affect up to 1 in 100 people)
  • Feelings of heaviness, pressure, tightness or pain in the chest, throat or other parts of the body. These symptoms can be intense but usually pass quickly.
  • If these symptoms persist or get worse (especially the chest pain):
    • See a doctor immediately.
    • In a very small number of patients, these symptoms can be caused by a heart attack.
  • Other uncommon side effects:
    • Visual disturbances (although these can be triggered by the migraine attack itself)
    • The heartbeat may speed up, slow down, or change rhythm.
    • A slight increase in blood pressure that may last up to 12 hours after ingestion.
    • If you notice any of these symptoms:
      • Inform your doctor or pharmacist.
• Rare side effects (may affect up to 1 in 1,000 people)
  • excessive sleepiness (somnolence)
  • Pain in the lower left side of your stomach and bloody diarrhea (ischemic colitis)
  • If you notice these symptoms:
    • Inform your doctor or pharmacist.
• Very rare side effects (may affect up to 1 in 10,000 people)
  • Heart problems, including chest pain (angina pectoris) and heart attack
  • Poor blood flow to the arms and legs causing pain and discomfort.
  • If you notice these symptoms:
    • Inform your doctor or pharmacist.
• If you get any side effects, talk to your doctor or pharmacist. This also applies to side effects that are not specified.

Naratriptan hydrochloride neuraxpharm® 2.5 mg, For use in migraines interactions

• Taking with other medicines
  • Tell your doctor if you are taking, have recently taken or might take any other medicines.
  • This also includes herbal or over-the-counter medicines.
  • Some medicines should not be taken with Naratriptan; others can cause side effects when taken with Naratriptan. You must tell your doctor if you are taking the following medicines:
    • another triptan or a 5-HT ₁ receptor agonist for migraine treatment.
      • Do not take Naratriptan at the same time as these medicines. Wait at least 24 hours after taking this medicine again.
    • ergotamine, which is also used to treat migraines, or similar medicines, e.g. B. methysergide. Do not take Naratriptan at the same time as these medicines. Stop taking these medicines at least 24 hours before taking Naratriptan. Wait at least 24 hours after taking these medicines again.
    • SSRIs (Selective Serotonin Reuptake Inhibitors) or SNRIs (Serotonin Norepinephrine Reuptake Inhibitors) used to treat depression. Taking these medicines at the same time as naratriptan may cause confusion, weakness and/or decreased coordination. Tell your doctor right away if you are affected in this way.
    • St. John's wort (Hypericum perforatum). Side effects may be more likely to occur when Naratriptan is taken together with herbal preparations containing St. John's wort.

Contraindications

• The medicine must not be used:
  • if you are allergic to naratriptan or any of the other ingredients of this medicine.
  • if you have heart problems such as a narrowing of the arteries in your heart (ischemic heart disease) or chest pain (angina pectoris), or if you have already had a heart attack.
  • if you have poor circulation in your legs that causes cramping pain when you walk (peripheral vascular disease).
  • if you have had a stroke or temporary reduced blood flow in the brain (also called transient ischemic attack).
  • if you have high blood pressure. You can take the film-coated tablets if your high blood pressure is slightly elevated and well controlled.
  • if you have severe kidney or liver disease.
  • with other migraine medications, including those containing ergotamine, or with similar medications such as methysergide, or with other triptans or 5-HT ₁ receptor agonists.
• If any of these contraindications apply to you:
  • Inform your doctor and do not take the preparation.

pregnancy and breast feeding period

• pregnancy
  • If you are pregnant, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine. There is limited information on the safety in pregnant women, although there is no evidence of an increased risk of birth defects. Your doctor may recommend that you do not take Naratriptan during pregnancy.
• lactation
  • Do not breast-feed your baby for 24 hours after taking it. If you express milk during this time, discard it and do not give it to your baby.

patient Naratriptan hydrochloride neuraxpharm® 2.5 mg, For use in migraines notes

• Warnings and Precautions
  • Please talk to your doctor or pharmacist before taking this medicine.
  • If you have certain other risk factors
    • if you are a heavy smoker or if you are on nicotine replacement therapy, and especially
    • if you are a man over 40 years old, or
    • if you are a woman who has gone through the menopause.
  • On very rare occasions, patients have developed serious heart problems after taking it, without any prior signs of heart disease.
  • If any of the above applies to you, it could mean that you are at an increased risk of developing heart disease, therefore
    • Let your doctor know so that your heart function can be checked before Naratriptan is prescribed for you.
  • If you are allergic to antibiotics called sulphonamides
    • If this is the case, you could also be allergic to naratriptan. If you know you are allergic to an antibiotic but not sure if it is a sulphonamide:
      • Tell your doctor or pharmacist before taking this medicine.
  • If you take the medicine frequently
    • Taking it too often can make your headache worse.
      • Tell your doctor if this applies to you. He may recommend that you stop taking it.
  • If you feel pain or tightness in your chest after taking it
    • These can be intense but usually pass quickly. If they don't go away quickly or if they get worse:
      • See a doctor immediately. See the "Side Effects" category for more information on these possible side effects.
  • If you are taking medicines for depression called SSRIs (selective serotonin reuptake inhibitors) or SNRIs (serotonin norepinephrine reuptake inhibitors).
    • Tell your doctor or pharmacist before taking this medicine.

• Driving and using machines
  • Drowsiness can occur from both the migraine attack and from taking . If this affects you, do not drive or use machines.