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NEURO LICHTENSTEIN N vitamin b1, b6 deficiency

Zentiva Pharma GmbH

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NEURO LICHTENSTEIN N vitamin b1, b6 deficiency

NEURO LICHTENSTEIN N coated tablets

Active ingredients: thiamine chloride hydrochloride (vitamin B1) 100 mg, pyridoxine hydrochloride (vitamin B6) 100 mg. 

 

NEURO LICHTENSTEIN N vitamin b1, b6 deficiency Application areas:

Systemic neurological diseases due to a proven deficiency of vitamins B1 and B6.

 

Contains lactose, sucrose (sugar), glucose and macrogol glycerol hydroxystearate.

Note leaflet.

For the treatment of systemic neurological diseases caused by a deficiency in vitamins B1 and B6.

NEURO LICHTENSTEIN N vitamin b1, b6 deficiency Active ingredients

  • 100 mg thiamine hydrochloride
  • 100 mg pyridoxine hydrochloride

Auxiliary materials

  • Lactose-1 water
  • talc
  • Cellulose, microcrystalline
  • Cellulose powder
  • Povidone K25
  • Partial glycerides, long-chain
  • Calcium behenat
  • Sucrose
  • Calcium carbonate
  • Clay, whiter
  • Arabic gum
  • Titanium dioxide
  • Glucose solution
  • Hypromellose
  • Stearic acid
  • Silica, finely divided
  • Cornstarch
  • Copovidone
  • Montan glycol wax
  • Macrogol 6000
  • Macrogol glycerol hydroxystearate
  • Erythrosine

NEURO LICHTENSTEIN N vitamin b1, b6 deficiency Indication / application

  • The preparation is a combination preparation from the group of B vitamins, which contains vitamin B 1 (thiamine chloride hydrochloride) and vitamin B 6 (pyridoxine hydrochloride) .
  • The drug is used to treat systemic neurological diseases caused by a proven deficiency in vitamins B 1 and B 6 .

dosage

  • Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.
  • Unless otherwise prescribed by your doctor, the usual dose is:
    • Unless otherwise prescribed, adults take 1 coated tablet once a day with a little liquid before or after meals.
    • If the deficiency is manifestly proven, the dose can be increased to 1 coated tablet up to 3 times a day after consultation with the attending physician.
  • After 4 weeks at the latest, the attending physician should decide whether the administration of vitamin B 1 and vitamin B 6 is still indicated in the high concentration present here. If necessary, you should switch to a preparation with a lower active ingredient strength in order to reduce the risk of neuropathy associated with vitamin B 6 .

 

  • If you take more than you should
    • Vitamin B 1 has a wide range of uses. So far, no overdose has been reported after taking vitamin B 1 .
    • Long-term ingestion (months to years) of vitamin B 6 in doses over 50 mg / day and short-term ingestion (2 months) in doses over 1 g / day can lead to nerve-damaging effects.
    • An overdose of vitamin B 6 is mainly indicated by sensory neuropathy, possibly with ataxia (coordination disorders). Extremely high doses can manifest as cramps.
    • Treatment of overdose
      • If doses above 150 mg / kg body weight have been taken acutely (all at once), artificially induced vomiting and the administration of activated charcoal are recommended. Vomiting is most effective in the first 30 minutes after ingestion. If necessary, intensive medical measures are required.

 

  • If you forget to take a dose
    • Do not take a double dose to make up for a forgotten dose.
    • Continue to use as described in the dosage instructions.

 

  • If you stop taking it
    • Please contact your treating doctor.

 

  • If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

NEURO LICHTENSTEIN N vitamin b1, b6 deficiency way

  • Swallow the coated tablet whole with some liquid before or after meals.

Side effects

  • Like all medicines, this medicine can have side effects, although not everybody gets them.
  • The frequency of side effects is based on the following categories:
    • Very common: affects more than 1 in 10 people
    • Common: affects 1 to 10 users in 100
    • Uncommon: affects 1 to 10 users in 1,000
    • Rare: affects 1 to 10 users in 10,000
    • Very rare: less than 1 user in 10,000
    • Not known: frequency cannot be estimated from the available data
  • Very rarely hypersensitivity reactions with sweating, palpitations, skin reactions with itching and hives (urticaria) or shock.
  • Long-term ingestion (several months to years) of daily doses of over 50 mg of vitamin B 6 and short-term ingestion (2 months) of doses of over 1 gram per day can be nerve-damaging and cause peripheral sensory neuropathy (discomfort mainly in the hands and feet).
  • If you get any side effects, talk to your doctor or pharmacist. This also applies to side effects that are not specified.

NEURO LICHTENSTEIN N vitamin b1, b6 deficiency Interactions

  • Taking the preparation together with other drugs
    • Tell your doctor or pharmacist if you are taking / using, have recently taken / used, or may take / use any other medicines.
    • The preparation is influenced as follows:
      • Weakening of the effect
        • Simultaneous administration of so-called pyridoxine antagonists (drugs that inter alia have an effect against vitamin B 6 , such as hydralazine, isoniazid (INH), cycloserine, D-penicillamine) can increase the need for vitamin B 6 .
        • Vitamin B 1 loses its effect when the anti-cancer drug (cytostatic) 5-fluorouracil is administered at the same time.
        • Stomach acid inhibitors reduce the absorption of vitamin B 1 .
        • Long-term treatment with the dehydrating agent furosemide can lead to a vitamin B 1 deficiency because more vitamin B 1 is excreted in the urine.
    • The preparation influences the effect of the following drugs:
      • Vitamin B 6 in daily doses of 5 mg or more can reduce the effect of levodopa (medicine used to treat Parkinson's disease).
  • Taking the drug with food, drink and alcohol
    • Alcohol and black tea reduce the absorption of vitamin B 1 .
    • Vitamin B 1 can be consumed at the same time as beverages containing sulfite, such as. B. Wine, degraded and thus ineffective.

Contraindications

  • Do not take the medicine
    • if you are allergic (hypersensitive) to thiamine chloride hydrochloride, pyridoxine hydrochloride or any of the other ingredients of this medicine.

NEURO LICHTENSTEIN N vitamin b1, b6 deficiency pregnancy and breast feeding period

  • Ask your doctor or pharmacist for advice before taking this medicine if you are pregnant or breast-feeding, if you suspect you may be pregnant, or are planning to become pregnant.
  • pregnancy
    • If you are pregnant, this medicinal product is only useful for treating a proven vitamin B 1 and B 6 deficiency due to the amount of active ingredients it contains.
    • Therefore, you should only take the drug after a careful risk-benefit assessment by the attending physician.
    • During pregnancy, the recommended daily intake of vitamin B 1 is 1.4 to 1.6 mg and of vitamin B 6 2.4 to 2.6 mg. The safety of using doses higher than the daily recommended dose has not yet been proven.
  • Breastfeeding
    • If you are breastfeeding, this medicinal product is only useful for treating a proven vitamin B 1 and B 6 deficiency due to the amount of active ingredients it contains. Vitamins B 1 and B 6 pass into breast milk.
    • Therefore, you should only take the drug after a careful risk-benefit assessment by the attending physician.
    • The recommended daily intake of vitamin B 1 is 1.4 to 1.6 mg during breastfeeding . The safety of using higher than the daily recommended doses of vitamin B 1 has not yet been proven. Vitamin B 6 is considered tolerable during breastfeeding. In view of the limited data available on the maximum recommended daily dose of vitamin B 6 during breastfeeding, it is recommended that you take a maximum of 20 mg of vitamin B 6 per day if you are breastfeeding .
    • High doses of vitamin B 6 can inhibit milk production.

NEURO LICHTENSTEIN N vitamin b1, b6 deficiency Patient information

  • Warnings and Precautions
    • Vitamin B 6 in daily doses of 50 mg or more can cause neuropathies, a disease of peripheral nerves, over a long period of time (months to years).
    • The main consequence of persistent abuse of vitamin B 6 is what is known as sensory axonal neuropathy, which can occur if high doses of vitamin B 6 are taken over a long period of time (months to years). Symptoms include numbness and worsening awareness of the position of the body, tremors in the hands and feet, and gradually progressive problems with coordination. The impairments generally go away as soon as the application exits.
    • If you have abnormal sensations such as If, for example, you notice a tingling sensation or numb feeling in your hands and feet, please contact your doctor. He or she will check the amount taken and, if necessary, stop taking the medicine.

 

  • Driving and using machines
    • There are no special precautions required.