NEURO VIBOLEX 200 pyridoxine, thiamine hydrochloride

CNP Pharma GmbH

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NEURO VIBOLEX 200  pyridoxine hydrochloride, thiamine hydrochloride

NEURO VIBOLEX 200 film-coated tablets

Active ingredients

  • 100 mg thiamine hydrochloride
  • 200 mg pyridoxine hydrochloride

Auxiliary NEURO VIBOLEX 200 pyridoxine hydrochloride, thiamine hydrochloride


  • Starch hydrolyzate
  • Methyl cellulose
  • Cellulose, microcrystalline
  • Crospovidone
  • Silica, finely divided
  • talc
  • Magnesium stearate
  • Methacrylic acid-methyl methacrylate copolymer (1: 1)
  • Triethyl citrate
  • Titanium dioxide
  • Macrogol 6000

Indication / NEURO VIBOLEX 200 pyridoxine hydrochloride, thiamine hydrochloride


  • The medicine is a vitamin preparation.
  • It is used to treat systemic neurological diseases caused by a proven deficiency in vitamins B 1 and B 6 .

NEURO VIBOLEX 200  pyridoxine, thiamine hydrochloride dosage

  • Always take the medicine exactly as directed. Please ask your doctor or pharmacist if you are not sure.
  • Unless otherwise prescribed by your doctor, the usual dose is:
    • Adults take 1 to 2 x 1 film-coated tablet per day.


  • Duration of application
    • The duration of therapy with the drug depends on the type and severity of the disease and is determined by the doctor.
    • After 4 weeks at the latest, the attending physician should decide whether the administration of vitamin B 6 and vitamin B 1 is still indicated in the present high concentration. If necessary, you should switch to a preparation with a lower active ingredient strength in order to reduce the risk of neuropathy associated with vitamin B 6 .


  • If you take more than you should
    • If more than 5 tablets are taken daily for 2 months, nerve damage can occur. However, even in daily doses of 50 mg or more, vitamin B 6 can cause neuropathies over a long period of time (months to years).
    • If sensitivity disturbances occur, a doctor should therefore be consulted. In these cases, the B vitamins should be discontinued and symptom-oriented measures taken if necessary.


  • If you forget to take a dose
    • Resume normal intake; do not make up for the forgotten dose with double the amount.


  • If you stop taking it
    • If the treatment is stopped prematurely, the symptoms of the disease may recur or worsen.


  • If you have any further questions on the use of the medicinal product, ask your doctor or pharmacist.

NEURO VIBOLEX 200  pyridoxine, thiamine hydrochloride way

  • The film-coated tablets are swallowed whole with sufficient liquid.

Side NEURO VIBOLEX 200  pyridoxine, thiamine hydrochloride effects

  • Like all medicines, the preparation can cause side effects, although not everybody gets them.
  • When evaluating side effects, the following frequencies are used as a basis:
    • Very common: more than 1 in 10 people
    • Common: less than 1 in 10, but more than 1 in 100 patients
    • Uncommon: less than 1 in 100, but more than 1 in 1000 patients
    • Rare: less than 1 in 1,000 but more than 1 in 10,000 patients
    • Very rare: less than 1 in 10,000 patients treated, or unknown
  • Possible side effects:
    • Hypersensitivity reactions can occur very rarely (hives (urticaria), rash, shock).
    • Nervous system
      • With long-term intake of daily doses of more than 50 mg vitamin B 6 and with short-term intake of doses in the gram range, peripheral sensory neuropathies (disease of the nerves with discomfort, e.g. tingling and pins and needles, mainly on the hands and feet) were observed.
  • Countermeasures:
    • If you experience side effects, stop taking the product and contact your doctor.
  • Please inform your doctor or pharmacist if you get seriously affected by any of the side effects listed, or if you notice side effects that are not listed.

NEURO VIBOLEX 200  pyridoxine, thiamine hydrochloride Interactions

  • When taking the preparation with other drugs
    • Please tell your doctor or pharmacist if you are taking / using or have recently taken / used any other medicines, including medicines obtained without a prescription.
    • Vitamin B 1 loses its effect if the anti-cancer drug (cytostatic) 5-fluorouracil is administered at the same time.
    • Taking antacids (medicines that bind stomach acid) at the same time reduces the absorption of vitamin B 1 .
    • Long-term treatment with the dehydrating agent furosemide can lead to a vitamin B 1 deficiency because more vitamin B 1 is excreted in the urine.
    • Simultaneous administration of so-called pyxridoxine antagonists (drugs that, among other things, have an effect against vitamin B 6 , such as hydralazine, isoniazid (INH), cycloserine, D-penicillamine) can increase the need for vitamin B 6 .
    • Vitamin B 6 can make L-dopa (a medicine used to treat Parkinson's disease) less effective.
  • Taking the drug with food and drink
    • Vitamin B 1 can be consumed at the same time as beverages containing sulfite, such as. B. Wine, degraded and thus ineffective. Alcohol and black tea can reduce the absorption of vitamin B 1 .


  • Do not take the medicine
    • if you are hypersensitive (allergic) to thiamine chloride hydrochloride (vitamin B 1 ), pyridoxine hydrochloride (vitamin B 6 ) or any of the other ingredients of the preparation.

pregnancy NEURO VIBOLEX 200  pyridoxine, thiamine hydrochloride and breast feeding period

  • Ask your doctor or pharmacist for advice before taking / using any medicine.
  • During pregnancy and breastfeeding, the daily vitamin requirement should be ensured with a balanced diet. Due to the amount of active ingredient, this medicinal product is only intended for the treatment of vitamin deficiency and may therefore only be taken after a careful risk / benefit assessment by the doctor. Systematic studies on the use of the drug during pregnancy are not available.
  • Vitamin B 1 and vitamin B 6 pass into breast milk.

Patient NEURO VIBOLEX 200  pyridoxine, thiamine hydrochloride information

  • Take special care when taking the drug
    • In the event of hypersensitivity to vitamin B 1 , the drug may only be taken after careful risk / benefit assessment under medical supervision.
    • After long-term daily doses of more than 50 mg pyridoxine hydrochloride (vitamin B 6 ) and short-term doses in the gram range, tingling and pins and needles were observed on the hands and feet (signs of peripheral sensory neuropathy or paresthesia). If you notice tingling sensations or pins and needles, please contact your doctor. He or she will check the amount taken and, if necessary, stop taking the medication.


  • Driving and using machines
    • There are no special precautions required.