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NEUROPLANT active St. John's wort depression tablets

Dr Willmar Schwabe GmbH & Co. KG

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NEUROPLANT active St. John's wort depression tablets

Neuroplant® AKTIV
600 mg / film-coated tablet
For adults (from 18 years).

Active ingredient:
St. John's wort dry extract

Areas of application:
light depressive disorders (light depressive episodes).

Herbal medicine for the treatment of depressive moods.

NEUROPLANT active St. John's wort depression tablets Active ingredients

  • 600 mg St. John's wort dry extract (3-7: 1); Extraction agent: methanol 80% (V / V)

NEUROPLANT active St. John's wort depression tablets Auxiliary materials

  • Ascorbic acid
  • Cellulose, microcrystalline
  • Croscarmellose sodium
  • Ferric oxide hydrate, black
  • Hypromellose
  • Stearic acid
  • Magnesium stearate (vegetable)
  • Sodium saccharine
  • Silica, like
  • Titanium dioxide
  • Vanillin

NEUROPLANT active St. John's wort depression tablets Indication / application

  • The preparation is a herbal medicine for depressive moods.
  • The medicine is used in
    • mild depressive episodes (disorders).

NEUROPLANT active St. John's wort depression tablets dosage

  • Always take the preparation exactly as directed. Please ask your doctor or pharmacist if you are not sure.
  • Unless otherwise prescribed by your doctor, the usual dose is:
    • Adults (from 18 years):
      • You should take 1 film-coated tablet once a day in the morning (equivalent to 600 mg St. John's wort extract per day).
  • Use in case of impaired kidney / liver function:
    • There are insufficient data for specific dosage recommendations in the case of impaired kidney / liver function.
  • Please talk to your doctor or pharmacist if you have the impression that the effect of this medicine is too strong or too weak.

 

  • Duration of application
    • Experience has shown that an intake of 4 - 6 weeks is necessary until the symptoms improve significantly; However, if the symptoms persist for more than 4 weeks or if they worsen despite the prescribed dosage, a doctor should be consulted again.

 

  • If you take more than you should:
    • Symptoms of overdose due to preparations containing St. John's wort extract have not yet become known. The side effects listed below may be more pronounced; in this case please notify your doctor. This can decide on any necessary measures.
    • After ingestion of massive overdoses, the skin should be protected from sunlight and UV radiation for a week due to possible increased sensitivity to light (limit your time outdoors, sun protection through covering clothing and use of sunscreen products with a high sun protection factor, so-called "sun blockers") the doctor should be informed.

 

  • If you forget to take a dose:
    • Next time do not take about double the amount, but continue taking as prescribed by your doctor or as described here.

NEUROPLANT active St. John's wort depression tablets way

  • To take.
  • Please swallow the film-coated tablets whole with sufficient liquid (preferably a glass of drinking water). Do not take film-coated tablets lying down.
  • Do not take film-coated tablets lying down. It can be taken independently of meals.

Side effects NEUROPLANT active St. John's wort depression tablets

  • Like all medicines, the preparation can have side effects.
  • The list includes all known side effects under treatment with St. John's wort dry extract, including those under higher doses or long-term therapy.
  • When taking this medicinal product, especially in fair-skinned people, skin areas that have been exposed to strong sunlight may react similarly to sunburn due to the skin's sensitivity to light (photosensitization).
  • In addition, gastrointestinal complaints, allergic reactions (e.g. reddening of the skin, swelling, itching), tiredness or restlessness can occur. The frequency of side effects is unknown.
  • If you observe one of the above-mentioned side effects, please inform your doctor so that he can decide on the severity and any necessary measures.
  • If you get any side effects, talk to your doctor or pharmacist. This also applies to side effects that are not specified.

Interactions NEUROPLANT active St. John's wort depression tablets

  • Interactions with other drugs
    • The medicinal product must not be used together with active substances from the following drug classes, in the breakdown and excretion of which certain liver enzymes (cytochrome P450-3A4, CYP2C9, CYP2C19) or a certain drug transport system (P-glycoprotein) are involved:
      • Drugs used in anti-HIV ("AIDS") treatment, such as indinavir and nevirapine;
      • Protease inhibitors for the treatment of hepatitis C infections, for example telaprevir;
      • Immunosuppressants such as ciclosporin and tacrolimus;
      • cell growth inhibiting drugs in cancer treatment, eg irinotecan; Imatinib and related substances (protein kinase inhibitors); Vinca alkaloids; Taxanes; Etoposide; Cyclophosphamide;
      • anticoagulants of the coumarin type, eg warfarin;
      • Medicines used to treat depression (antidepressants). The effectiveness of other drugs can be weakened if the preparation is taken at the same time. If used at the same time, regular medical therapy controls should be carried out. These drugs include, for example:
        • Digoxin,
        • Fexofenadine,
        • Benzodiazepines and related substances,
        • Methadone,
        • Simvastatin,
        • Finasteride.
    • Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
    • The increased activity of drug-degrading liver enzymes normalizes within a week of stopping the drug.
    • If certain active substances for the treatment of depression (nefazodone, paroxetine, sertraline), buspirone or certain active substances for the treatment of migraines (triptans) are taken at the same time, their pharmacological effects may be increased. In individual cases, undesirable effects such as nausea, vomiting, anxiety, restlessness and confusion may occur more intensely (serotonergic syndrome).
    • Women who use hormonal contraceptives at the same time as this medicine may have bleeding between periods and the safety of contraception may be reduced.
    • With simultaneous treatment with other drugs that increase the skin's sensitivity to light, the undesirable effects on the skin may be intensified.
    • Before planned operations, it should be clarified whether there may be any interactions between the anesthetics and those of this drug. If necessary, the preparation should be discontinued.

NEUROPLANT active St. John's wort depression tablets Contraindications

  • The medicine must not be taken
    • in severe transient depressive disorders, as insufficient data are available on this
    • during pregnancy.
    • in severe transient depressive disorders;
    • The medicinal product must not be used together with active substances from the following drug classes, in the breakdown and excretion of which certain liver enzymes (cytochrome P450-3A4, CYP2C9, CYP2C19) or a certain drug transport system (P-glycoprotein) are involved:
      • Drugs used in anti-HIV ("AIDS") treatment, such as indinavir and nevirapine;
      • Protease inhibitors for the treatment of hepatitis C infections, for example telaprevir;
      • Immunosuppressants such as ciclosporin and tacrolimus;
      • cell growth inhibiting drugs in cancer treatment, eg irinotecan; Imatinib and related substances (protein kinase inhibitors); Vinca alkaloids; Taxanes; Etoposide; Cyclophosphamide;
      • Anti-coagulants of the coumarin type, e.g. warfarin.
    • Furthermore, the drug must not be taken together with other drugs used to treat depression (antidepressants).
    • Do not use in case of hypersensitivity to the medicinally active ingredient or any of the other ingredients, or if the skin is known to be hypersensitive to light.

pregnancy and breast feeding period NEUROPLANT active St. John's wort depression tablets

  • pregnancy
    • The preparation must not be taken during pregnancy due to insufficient examinations. Animal experiments show ambiguous results. The potential risk to humans is unknown. Women of childbearing potential must use effective contraception during treatment and for at least two weeks after treatment (women using hormonal contraceptives should take additional measures.
  • Breastfeeding
    • There is insufficient information on whether components of the active substance or their metabolites pass into breast milk. Breastfeeding women should not take the drug as insufficient research is available.

NEUROPLANT active St. John's wort depression tablets Patient information

  • Take special care when taking the drug
    • When can you only use the preparation after consulting your doctor or pharmacist?
      • Medicines containing St. John's wort can affect the metabolism of other medicines taken at the same time. This can result in a reduced and / or shortened effect for the medicinal product concerned. Therefore it may be necessary to adjust the dosage of these medicines.
    • What should be considered in children and adolescents?
      • The use of the drug in children and adolescents up to 18 years of age is not recommended as insufficient data are available on this.
    • What else do you need to look out for?
      • While using the drug, you should avoid intense UV radiation (long sunbathing, sunlamps, solariums).
      • If you use hormonal contraceptives such as the "birth control pill" or hormone implants and take this medicine at the same time, you may experience intermenstrual bleeding and the safety of the contraception may be reduced. You should therefore take additional contraceptive measures.

 

  • Driving and using machines
    • Insufficient studies are available on the effect of the drug on the ability to drive and use machines.