What is a probiotic?
"Living microbial additive which favorably affects the host by improving the intestinal microbial balance" - R. Fuller.
Effects of probiotics on the barrier function of the intestinal epithelium
Breaking the epithelial barrier:
The increased permeability is associated with various diseases:
inflammatory bowel diseases,
Syndrome irritable bowel syndrome;
chronic inflammation (autism, migraine, metabolic syndrome);
probiotic bacteria have the ability to improve barrier function; the
effects are specific to each strain.
History of probiotics
1st generation probiotics from 1930:
A bacterial strain was used that was thought to exist in all parts of the gut.
2nd generation probiotics from 1990:
A more in-depth and comprehensive study of the gut. Science is trying to categorize the diversity of intestinal bacteria and decode them as chemical substances.
New: multi-species (multistem):
Current meta-analyzes have shown that multi-species probiotics are more effective than bacterial products of one species;
The specific subspecies are selected according to their specific functions;
The "ONE IS SUITABLE FOR EVERYONE" concept is not valid.
3rd generation - at the beginning of the third millennium:
Molecular genetic analysis of bacterial strains and their characteristics allow to detect differences between species and subspecies.
16S rDNA analysis provides information on the diversity of bacteria: 2010 - about 5,000 phylotypes are known in the human gut. About 36,000 strains can be differentiated. Incredible opportunities open up before us!
Omni Biotic PANDA Quality of probiotics:
OPROM (Osterreichische Gesellschaft fur Probiotische Medizin - Austrian Society for Probiotic Medicine) publishes precise quality standards for probiotics that can be used in practice and should be used for the prevention of certain diseases.
Omni Biotic PANDA Quality standards:
- Sustainability in GIT;
- Active and suppressing pathogens;
- Intestinal colonization;
- Production of cytokines (immunomodulatory agents);
- Scientific evidence in clinical trials.
The food supplement Omni Biotic PANDA contains selected probiotic strains, specially designed for children, babies and expectant mothers during pregnancy. The product regulates the activity of the immune system and supports the natural intestinal flora of the child.
The multi-strain Omni Biotic PANDA is the first scientifically developed probiotic to treat a non-existent imbalance between the mother's immune system during the last two months of pregnancy.
Due to the fact that PANDA probiotic is used in newborns from the first day after birth (and throughout the first year of life) - the immunological modulation of TH1 and TH2 homeostasis may be affected.
Based on this study, B. bifidum, B. infantis and Lc were selected. Lactis (due to their good IL-10-inducing activity and also effective inhibition of IL-5 and IL-13), which are part of multi-strain probiotics in a clinical study for the basic prevention of allergic diseases by probiotic bacteria.
Omni Biotic PANDA Active ingredients:
Lactococcus lactis W58;
Bifidobacterium lactis W52;
Bifidobacterium bifidum W23.
How to use Omni Biotic PANDA:
To support the health of the colon, take 1 sachet daily. To activate the bacterial strains, pour the sachet into a glass of water and wait 15 minutes before drinking it.
Recognized as safe by the FDA.
With NIZO * Status in Europe.
* company for research of the quality of food, probiotics and proteins; founded in 1948.
Omni Biotic products are stable and have a shelf life of 2 years at room temperature.
The amount of live bacteria is described on the package and is kept stable until the expiration date.
3. Activity The
bacterial strain is active within 24 hours of dissolution, which stimulates its growth and development.
If taken later, it remains in the intestine, but is no longer fully active and cannot function fully.
4. Immunologically relevant strains
Probiotic strains differ in their production of cytokines and are used in specific diseases.
Proven modulation of the immune system due to the intake of probiotics;
Cytokine production due to probiotic strains has been tested in vitro in product studies.