Oral glucose tolerance test, oGTT, test for glucose

INFECTOPHARM Arzn.u.Consilium GmbH

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Oral glucose tolerance test, oGTT, test for glucose, Glucose test oGTT InfectoPharm

For diagnostic confirmation or to exclude a suspicion of diabetes mellitus or impaired glucose tolerance.

 

active Oral glucose tolerance test, oGTT, test for glucose ingredients

 

  • 275 mg glucose-1 water

ingredients

  • 1.5 mg benzoic acid
  • water, purified
  • Citric acid monohydrate
  • glycerol

 

Indication Oral glucose tolerance test, oGTT, test for glucose:

 

  • The preparation is an oral glucose tolerance test for diagnostic confirmation or to exclude suspicion of diabetes mellitus or impaired glucose tolerance.

 

Dosage Oral glucose tolerance test, oGTT, test for glucose:

 

  • Always take this medicine exactly as described or as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.
  • Adults receive 300 ml solution with 75 g anhydrous glucose, pregnant women 400 ml solution with 100 g anhydrous glucose and children a volume containing 1.75 g anhydrous glucose/kg body mass, but no more than 75 g anhydrous glucose (10 ml solution contain 2, 5 g anhydrous glucose).
  • Evaluation of the test:
    • Blood glucose limits for the oral glucose tolerance test after exposure to 75 g anhydrous glucose (children: 1.75 g anhydrous glucose/kg body mass) according to WHO recommendations:
      • diabetes mellitus
        • thoroughbred
          • venous
          • capillary
        • plasma
          • venous
          • capillary
      • Impaired glucose tolerance
        • thoroughbred
          • venous
          • capillary
        • plasma
          • venous
          • capillary
    • Limits for pregnant women:
      • diabetes mellitus
        • fasting value:
          • Venous plasma glucose concentration >/=105 mg/dl or >/= 5.8 mmol/l
        • 1 hour value
          • Venous plasma glucose concentration >/= 190 mg/dl or >/= 10.5 mmol/l
        • 2 hour value
          • Venous plasma glucose concentration >/= 165 mg/dl or >/= 9.1 mmol/l
        • 3 hour value
          • Venous plasma glucose concentration >/= 145 mg/dl or >/= 8.0 mmol/l
  • A notice:
    • Glucose tolerance can be influenced by the following disruptive factors:
      • medication
      • potassium deficiency
      • magnesium deficiency
      • hyperlipoproteinemia
      • liver cirrhosis
      • hyperthyroidism
      • severe heart failure
      • metabolic acidosis (uremia)
      • Stress effects (e.g. heart attack, operations, trauma)
      • pregnancy
      • long bed rest
      • Menstruation and three days before and after.
    • A pathological result can be simulated by the following diseases and factors:
      • duodenal ulcer
      • Condition after Billroth II operation
      • potassium deficiency
      • magnesium deficiency
      • hepatic dysfunction
      • Medications (such as ovulation inhibitors, laxatives, sulfonamide derivatives, etacrynic acid)
      • state of hunger.
    • A negative result despite a diabetic metabolic condition can be faked by the following diseases or factors:
      • acute enteritis
      • regional enteritis
      • Irritable colon
      • ulcerative colitis
      • Glucose-galactose intolerance
      • disaccharidase deficiency
      • Whipple's disease
      • tuberculosis
      • parasite infestation
      • Drugs such as caffeine, reserpine, biguanides, MAO inhibitors, blood glucose-lowering sulfonamide derivatives, gonadotropins, medium-chain fatty acids.
  • If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
way :
  • The solution must be drunk within 5 minutes.
  • Preparation of the patient:
    • before the test, the usual eating habits must be observed for at least 3 days (at least 150-200 g carbohydrates)
    • For at least 3 days prior to the test, non-essential medications that may interfere with glucose tolerance should be discontinued
    • normal physical activity should be resumed before the test; bedridden or excessive physical activities are excluded
    • the interval to menstruation should be at least 3 days
    • after ten to sixteen hours of fasting - no eating, no drinking (other than water), no smoking, no physical exertion - the test should be performed by 9:00 a.m.
    • If the conditions for preparing the patient are not observed, the results of the test may be inaccurate.
  • Carrying out the test:
    • The test should be performed with the patient seated as follows:
      • Taking blood to determine the fasting blood sugar level
      • Drink the test solution within 5 minutes
      • Blood sampling 60, 120 and 180 minutes after ingestion
      • You should not smoke or do any physical activity during the test.
      • In order to detect a change in what is known as the normal renal threshold for glucose, the glucose in the urine should be determined after the last blood sample was taken.
Side effects :
  • Like all medicines, this medicine can cause side effects, although not everybody gets them.
  • Side effects can occur:
    • very rarely allergic reactions, e.g. B. Skin redness
    • rarely stomach pressure and nausea
    • occasional hypoglycemic symptoms occurring during the test or later, with decreased responsiveness.
  • What countermeasures should be taken in the event of side effects?
    • The risk of hypoglycaemia can be reduced by giving some sugar or a meal containing carbohydrates after the test.
  • If you get any side effects, talk to your doctor or pharmacist. This also applies to side effects that are not specified.

 

Oral glucose tolerance test, oGTT, test for glucose Interactions :

 

  • Taking with other medicines
    • Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.
    • The test is affected by concomitant therapy with medications that may affect glucose tolerance, e.g. e.g.:
      • nonsteroidal anti-inflammatory drugs
      • glucocorticoids
      • laxative
      • Drugs used to lower high blood pressure (other than ACE inhibitors)
      • nicotinic acid derivatives
      • nitrazepam
      • phenothiazines
      • oral contraceptives
      • thyroid hormones
      • Thiazide and furosemide type saluretics
      • tranquilizers and sedatives.
    • Please note that this information may also apply to recently used medicines. If this is possible without risk, these medications should be discontinued at least three days before the test. If a drug cannot be dispensed with, the test result requires a differentiated interpretation.
Contraindications :
  • The drug must not be taken
    • if you are allergic to glucose monohydrate or any of the other ingredients of this medicine.
    • in manifest diabetes mellitus
    • with feverish infections
    • in acute gastrointestinal diseases
    • with a severely reduced general and nutritional status.
Pregnancy and lactation :
  • If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
Patient Notes :
  • Warnings and Precautions
    • Please talk to your doctor or pharmacist before taking this medicine.
    • What precautions should be taken?
      • Occasionally, during the test or later, hypoglycemic symptoms can occur that affect the patient's condition (reduced ability to react).
      • To avoid symptoms of hypoglycaemia, a carbohydrate-rich meal should be eaten immediately after the test.
    • children and young people
      • No special notices.

 

  • Ability to drive and use machines
    • The ability to drive, use machines, or work without a secure footing may be impaired by the onset of hypoglycaemic symptoms.