- Pain medication, metamizol magnesium. The active substance used in the Pyralgina pyrexia 500mg product is metamizol magnesium. It is a non-opioid painkiller with analgesic and antipyretic effects.
Composition Pain medication Pyralgina pyrexia 500mg:
The active substance of the drug: metamizol magnesium. One sachet contains 500mg of metamizol magnesium in the form of magnesium hexamethane metamizol and other components: mannitol, povidone K29 / 32, sodium saccharin, orange flavor, orange yellow (E110).
Action Pain medication:
The drug in the form of granules for the preparation of an oral solution Pyralgina Fever 500mg is a medicinal product containing a derivative of pyrazolone, i.e. metamizol magnesium. Metamizol has analgesic and antipyretic properties, and also has a relaxant effect on smooth muscles. A solution with orange flavor.
Pain medication Application:
Pyralgina medicinal product Fever 500mg indicated for use in the treatment of fever. The drug is recommended to use in cases where other agents are ineffective or there are contraindications to their use.
Additional information Pain medication:
Keep the product out of reach of children at room temperature. It contains orange yellow, or a dye that causes some people to have an allergic reaction. One sachet contains 0.04 carbohydrate exchanger. One sachet contains 0.2mmol (4.58mg) of sodium.
Pain medication Contraindications:
Do not use in the case of hypersensitivity to any component of the drug, other derivatives of pyrazolone and pyrazolidine. Do not use in the case of a recognized analgesic asthma syndrome or known intolerance to analgesics, which manifests itself as urticaria, angioedema (eg bronchial spasms or other anaphylactoid reactions to salicylates, paracetamol, other non-opioid analgesics, also non-steroidal anti-inflammatory drugs). Do not use in cases of bone marrow dysfunction or changes in the morphological image of the blood. Do not use in the case of acute renal or hepatic failure, acute hepatic porphyria, congenital deficiency of glucose-6-phosphate dehydrogenase. Do not use during pregnancy and lactation. Do not use in combination with other pyrazolone derivatives.
Adverse reactions may occur during use. If you get the following symptoms, stop taking the medicine and get medical attention: severe allergic reaction (anaphylactic) - rarely swelling of the face, lips, tongue and / or throat, which may cause difficulty in swallowing or breathing; very rare severe bronchospasm; skin and mucosal changes such as pruritus, burning, redness, hives; anaphylactic shock (life-threatening decrease in blood pressure, asthenia, syncope) - frequency unknown. The drug should be immediately discontinued and consult a physician if the following side effects occur: Stevens-Johnson syndrome (blisters affecting erosions, on the mucous membranes of the mouth, conjunctivitis, genitals); Lyell's syndrome (toxic epidermal necrolysis, erythematous blisters within the skin and mucous membranes leading to large areas of the epidermis and exposing large areas of the skin); pancytopenia (significant reduction in the number of all blood cells: red and white blood cells and platelets, manifesting as general malaise, fever, signs of infection, hematomas, bleeding, pale skin); agranulocytosis (total or almost complete disappearance of granulocytes in the blood) manifested by: high fever, chills; sore throat, difficulty in swallowing and inflammation of the oral mucosa, nose, throat, genital and rectum; increased OB; not always normal values of hemoglobin, erythrocytes and platelets, although they are usually normal; slightly enlarged lymph nodes and spleen, although they are usually unchanged. A single report indicates that the risk of agranulocytosis may increase with metamizol for more than one week. Other side effects: uncommon - drug-induced rash (transient various types of rash: papular, spotted, pustular, erythematous); excessive reduction of blood pressure; rarely - maculopapular changes; leukopenia (reduction in the number of white blood cells); very rarely - analgesic asthma, asthma attacks; thrombocytopenia (hematomas, bleeding); sudden deterioration of renal function with proteinuria, oliguria or anuria; acute renal failure; interstitial nephritis; frequency unknown - nausea, vomiting, abdominal pain, stomach irritation, diarrhea, dry mouth; liver damage; headaches and dizziness; hemolytic anemia, aplastic anemia, bone marrow damage, sometimes fatal. In patients deficient in glucose-6-phosphate dehydrogenase, the drug causes haemolysis of the blood cells; red urine (after using very high doses of metamizol).
Pain medication Dosage:
Use as directed by your doctor or as directed on the leaflet. Dissolve the contents of the sachet in a glass of water, drink while eating or immediately after a meal. It is recommended to use the lowest effective doses. In adults, in the case of fever and occasional pain: take 1-2 sachets once (0.5g-1g of metamizol). The maximum single dose is two sachets (1g metamizol), while the maximum daily dose is 6 sachets (3g metamizol). You should consult your doctor when there has been no improvement after 3-5 days of using the medicine.