PARACETAMOL x 30 tablets

Composition:
1 tablet. It contains 500 mg of paracetamol. Action: The drug analgesic and antipyretic, primarily by inhibiting prostaglandin cyclooxygenase in the central nervous system in the hypothalamus, which decreases the concentration of prostaglandins. Well absorbed from the gastrointestinal tract, the maximum blood concentration reaches approximately 0.5-2 h, excreted in body fluids and internal organs, approximately 25% bound to plasma proteins. T _0.5 is 2-3 h. It is metabolised in the liver, cause there microsomal enzyme induction. It is excreted in the urine as glucuronide and sulfate, and after coupling with cysteine. In patients with renal failure linked paracetamol accumulates in the blood. At high doses produced in the body of N-acetyl-p-benzoquinone responsible probably for causing liver damage. Indications: As a medicine antipyretic (fever, eg. In the course of infectious diseases, colds, flu) and analgesic in pain of various origins (headache - including migraine, ear, dental, menstrual, neuralgia, rheumatic pain, myofascial, bone, postoperative and others). Dosage: Dorśli: 1-2 tablets. once; the dose can be repeated more often than every 4 hours 2-4 times a day. With long-term use does not przekraczć 2.6 g / day. In the treatment of cancer pain usually about 10 mg / kg / dose every 4 h often in combination with drugs having different mechanism of action. Children over 3 m.ż .: 10 mg / kg body weight not less than 6 h. Do not take for more than a few days without medical advice. Taken orally; adoption before eating increases the efficiency of the drug.