SODIUM PHOSPHATE Braun MPC Infusion Solution Concentrate

Pack size:20 x 20 ml Dosage form:Infusion solution concentrate

Sodium Phosphate Brown Concentrate. Indications: Used to correct phosphate deficiencies.

For risks and side effects, read the package insert and ask your doctor or pharmacist.


PACKAGE LEAFLET: INFORMATION FOR THE USER

Sodium Phosphate Brown Concentrate for the preparation of an infusion solution.
Active ingredients: Sodium monohydrogen phosphate dodecahydrate, sodium dihydrogen phosphate dihydrate.

Read the entire package leaflet carefully before you start taking/using this medicine.

• Keep this leaflet. You may want to read it again later.
• If you have any further questions, ask your doctor or pharmacist.
• This medicine has been prescribed for you personally. Do not share it with anyone else. It may harm others, even if they have the same symptoms as you.
• If any of the side effects listed affect you seriously or if you notice side effects not listed in this leaflet, please inform your doctor or pharmacist.

1. WHAT IS SODIUM PHOSPHATE BROWN AND WHAT IS IT USED FOR?
2. WHAT SHOULD YOU CONSIDER BEFORE USING SODIUM PHOSPHATE BROWN?
3. HOW SHOULD SODIUM PHOSPHATE BROWN BE USED?
4. WHAT SIDE EFFECTS ARE POSSIBLE?
5. HOW SHOULD SODIUM PHOSPHATE BROWN BE STORED?
6. MORE INFORMATION

1. WHAT IS SODIUM PHOSPHATE BROWN AND WHAT IS IT USED FOR?

Sodium Phosphate Brown is a concentrated solution of sodium phosphate for the intravenous administration of phosphate (intravenous = administration via a vein drip). Sodium Phosphate Brown is used to correct phosphate deficiencies. Sodium Phosphate Brown is a medicine that will be administered to you by a doctor or medical professional.

2. WHAT SHOULD YOU KNOW BEFORE TAKING/USE SODIUM PHOSPHATE BROWN?

Sodium Phosphate Brown must not be used if:

• increased phosphate levels in the blood (hyperphosphatemia),
• increased sodium levels in the blood (hypernatremia),
• low calcium levels in the blood (hypocalcaemia),
• Disorders of kidney function.

Special care is required when using Sodium Phosphate Brown:
in diseases that require a restrained sodium intake, such as

• Heart failure (cardiac insufficiency),
• Fluid accumulation in the tissue (generalized edema),
• Fluid accumulation in the lungs (pulmonary edema),
• high blood pressure (hypertension),
• pregnancy-related conditions with high blood pressure, cramps and fluid accumulation in the tissue (eclampsia),
• severe kidney dysfunction (renal failure).

Serum ionogram checks are required. During treatment with Sodium Phosphate Brown, blood phosphate levels and the amount of phosphate excreted in the 24-hour urine collection should be checked once a week if necessary. Since high phosphate intake can cause low blood calcium levels and calcium deposits in tissues, regular blood calcium and phosphate checks are necessary if daily intake exceeds 50 mmol. When administering high doses of phosphate, simultaneous calcium intake may be necessary. Since the solution contains 1 mol of sodium for every 0.6 mol of phosphate, the sodium intake must be taken into account when balancing electrolytes. When replacing phosphate as part of intravenous (parenteral) nutrition, it should be noted that various parenteral nutrition solutions (including fat emulsions) already contain phosphate.

When taking/using Sodium Phosphate Brown with other medicines:
Please inform your doctor or pharmacist if you are taking/using or have recently taken/used any other medicines, including medicines obtained without a prescription. Sodium Phosphate Brown is physically and chemically incompatible with solutions containing calcium and magnesium.

Pregnancy and breastfeeding
Please inform your doctor before treatment with Sodium Phosphate Brown if you are pregnant or breastfeeding. Since there is insufficient data on the safety of use during pregnancy and breastfeeding, caution is advised. Your doctor will only prescribe this medicine if they consider it absolutely necessary.

Driving and using machines:
Sodium Phosphate Brown has no influence on the ability to drive or operate machinery.

3. HOW SHOULD SODIUM PHOSPHATE BROWN BE TAKED/USED?

This medicine will be administered to you by a doctor or medical specialist.

Dosage:
The dosage depends on the need for correction. The average requirement of an intensive care patient is approximately 50–70 mmol phosphate per day, or 0.7–1 mmol/kg body weight per day.

Maximum infusion rate:
No more than 20 mmol phosphate should be administered per hour.

Method of administration:
Intravenous use. Only use diluted as an additive to infusion solutions! In general, the calculated amount of Sodium Phosphate Brown is administered in 250 ml of fluid. If fluid is depleted, a larger amount of carrier solution can be used. For infusion into so-called peripheral veins (usually veins in the hand or forearm), Sodium Phosphate Brown must be diluted so that the total concentration of dissolved substances does not exceed a certain level (800 mmol/l). Particular care must be taken when administering strictly into a vein (intravenously), as administering it beyond the vein into the surrounding tissue (paravenously) can lead to hardening and calcium deposits in the tissue.

If you use more Sodium Phosphate Brown than you should:
Overdose can lead to increased phosphate levels in the blood with subsequent kidney damage due to deposition of calcium phosphate, deposition of calcium phosphate in other tissues (e.g. skin, cornea of the eye, lungs), reduced calcium levels in the blood and increased sodium levels in the blood.

Countermeasures in severe cases:
Hemodialysis.

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

4. WHAT ARE THE POSSIBLE SIDE EFFECTS?

Like all medicines, Sodium Phosphate Brown can cause side effects, although not everybody gets them.

Metabolism and nutrition disorders:
Frequency not known: When used, increased sodium levels in the blood (hypernatremia) may occur.

Reporting of side effects:
If you notice any side effects, contact your doctor or pharmacist. This also applies to side effects not listed in this package leaflet. You can also report side effects directly to the Federal Institute for Drugs and Medical Devices, Dept. Pharmacovigilance, Kurt-Georg-Kiesinger Allee 3, D-53175 Bonn, By reporting side effects, you can help provide more information on the safety of this medicine.

5. HOW SHOULD SODIUM PHOSPHATE BROWN BE STORED?

Keep medicines out of the sight and reach of children. Do not use this medicine after the expiry date which is stated on the carton or container after “%%%Use by”%%% or “%%%EXP”%%%. The expiry date refers to the last day of that month. Storage conditions: This medicine does not require any special storage conditions. Do not use Sodium Phosphate Brown if you notice any cloudiness or particles in the solution, or if the ampoule is leaking. This medicine should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. This measure helps to protect the environment.

6. FURTHER INFORMATION

What Sodium Phosphate Brown contains:
The active ingredients are: sodium monohydrogen phosphate dodecahydrate and sodium dihydrogen phosphate dihydrate. 20 ml of concentrate for solution for infusion contains: Sodium monohydrogen phosphate dodecahydrate (Ph. Eur.) 3.050 g Sodium dihydrogen phosphate dihydrate (Ph. Eur.) 0.462 g. 1 ml contains 1 mmol Na+ and 0.6 mmol PO43. The other ingredient is: Water for injections.

What Sodium Phosphate Brown looks like and contents of the pack:
Sodium Phosphate Brown is a concentrate for solution for infusion, i.e. it is diluted in a suitable carrier solution before administration. It is a clear, colorless aqueous solution. Container: Ampoule made of colorless polyethylene. Contents: 20 ml. It is available in packs of 20 ampoules.

Pharmaceutical Entrepreneur and Manufacturer:
B. Braun Melsungen AG
Carl-Braun-Straße 1
34212 Melsungen

Postal Address:
34209 Melsungen


This package leaflet was last revised in May 2025.

Source: Information from the package leaflet.
Version: 08/2025

Areas of application: is used to remedy phosphate deficiency conditions.

To remedy phosphate deficiency conditions