THIOCTACID, alpha lipoic acid 600mg, paraesthesia

MEDA Pharma GmbH & Co. KG

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THIOCTACID, paraesthesia 600 HR film-coated tablets, alpha lipoic acid 600mg


Active ingredient: DL-alpha lipoic acid

For paraesthesia in diabetic polyneuropathy.

active paraesthesia ingredients

  • 600 mg DL-α-lipoic acid


THIOCTACID, alpha lipoic acid 600mg, paraesthesia excipients


  • Hyprolose, low-substituted
  • magnesium stearate
  • hyprolose
  • hypromellose
  • Macrogol 6000
  • talc
  • titanium dioxide
  • Quinoline yellow, aluminum salt
  • Indigodisulfonic acid, aluminum salt

Indication/ THIOCTACID, alpha lipoic acid 600mg, paraesthesia Application

  • Thioctic acid (alpha-lipoic acid) is a substance formed in higher organisms in the body's own metabolism, which influences certain metabolic processes in the body. In addition, thioctic acid has (antioxidative) properties that protect the nerve cell from reactive breakdown products.
  • The drug is used in
    • Paraesthesia with diabetic nerve damage (polyneuropathy).

THIOCTACID, alpha lipoic acid 600mg, paraesthesia dosage

  • Always take this medicine exactly as described or as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.
  • The recommended dose is:
    • 1 film-coated tablet of thioctic acid (equivalent to 600 mg thioctic acid) as a single dose about 30 minutes before the first meal.


  • duration of use
    • Since diabetic nerve damage is a chronic disease, you may need to take thioctic acid on a long-term basis.
    • Your doctor will decide in individual cases.
    • Please talk to your doctor or pharmacist if you have the impression that the effect is too strong or too weak.


  • If you take more than you should
    • Overdose may cause nausea, vomiting and headaches.
    • In individual cases, severe, e.g. T. life-threatening symptoms of poisoning observed (such as generalized seizures, derailment of the acid-base balance with lactic acidosis, severe blood clotting disorders).
    • Therefore, if a significant overdose is suspected (e.g. more than 10 tablets of 600 mg in adults and more than 50 mg/kg body weight in children), immediate hospitalization and the initiation of measures according to the general treatment principles for cases of poisoning are required.


  • If you forget to take a dose
    • Do not take a double dose to make up for a forgotten dose.


  • If you have any further questions on the use of the medicine, ask your doctor or pharmacist.


THIOCTACID, alpha lipoic acid 600mg, paraesthesia way

  • The film-coated tablets should be swallowed whole and with sufficient liquid on an empty stomach. Simultaneously ingesting food can impede the passage of thioctic acid into the bloodstream. It is therefore particularly important in patients who also have a prolonged gastric emptying time that the dose is taken half an hour before a meal/breakfast.

side THIOCTACID, alpha lipoic acid 600mg, paraesthesia effects

  • Like all medicines, this medicine can cause side effects, although not everybody gets them.
  • Very rare (affects less than 1 user in 10,000):
    • Gastrointestinal symptoms such as nausea, vomiting, stomach and intestinal pain and diarrhea
    • taste disorders
    • Allergic reactions such as skin rash, hives (urticaria) and itching
    • Due to improved glucose utilization, the blood sugar level can drop. Symptoms like hypoglycaemia with dizziness, sweating, headaches and visual disturbances were described.
  • countermeasures
    • If you notice the side effects mentioned above, thioctic acid should not be taken again. Notify your doctor so he can decide on the severity and any further action that may be needed.
    • At the first sign of a hypersensitivity reaction, the drug should be discontinued and a doctor contacted immediately.
  • If you get any side effects, talk to your doctor, pharmacist or nurse. This also applies to side effects that are not specified.

THIOCTACID, alpha lipoic acid 600mg, paraesthesia interactions

  • Taking together with other medicines
    • Please tell your doctor or pharmacist if you are using, have recently used or might use any other medicines. It cannot be ruled out that the simultaneous use of thioctic acid leads to a loss of effectiveness of cisplatin (a cancer drug).
    • Thioctic acid easily forms chemical compounds with metals (metal chelator) and should therefore not be given at the same time as metal compounds (e.g. iron preparations, magnesium preparations, milk products due to the calcium content) for fundamental reasons, as this can lead to a loss of effectiveness. If the entire daily dose of thioctic acid is taken 30 minutes before breakfast, iron and magnesium supplements can be taken at noon or in the evening.
    • The blood sugar-lowering effect of insulin or oral antidiabetics can be increased. Close blood sugar monitoring is therefore indicated, particularly in the initial stages of therapy with thioctic acid. In individual cases, it may be necessary to reduce the insulin dose or the dose of the oral antidiabetic in accordance with the instructions of the attending physician in order to avoid symptoms of hypoglycaemia.
  • Take with food, drink and alcohol
    • The regular consumption of alcohol represents a significant risk factor for the development and progression (progression) of neuropathic diseases and can thus also impair the success of treatment with thioctic acid. Therefore, patients with diabetic polyneuropathy are generally recommended to avoid the consumption of alcohol as far as possible. This also applies to therapy-free intervals.

THIOCTACID, alpha lipoic acid 600mg, paraesthesia Contraindications

  • The medicine should not be taken
    • if you are allergic to thioctic acid or any of the other ingredients.

pregnancy THIOCTACID, paraesthesia, alpha lipoic acid 600mg and breast feeding period

  • If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine
  • It is in accordance with the general principles of pharmacotherapy to only use drugs during pregnancy and breastfeeding after carefully weighing the benefits and risks.
  • Pregnant and breastfeeding women should only undergo treatment with alpha-lipoic acid after careful recommendation and monitoring by their doctor, as there is no experience with this group of patients to date. Special studies on animals have not produced any indications of fertility disorders or teratogenic effects.
  • Nothing is known about a possible transfer of alpha-lipoic acid into breast milk.



patient THIOCTACID, alpha lipoic acid 600mg, paraesthesia notes

  • Warnings and Precautions
    • Please talk to your doctor, pharmacist or nurse before taking this medicine.
    • children and young people
      • Children and adolescents should be excluded from treatment as there is no clinical experience in this age group.


  • Driving and using machines:
    • There are no special precautions required.