• 600 IU of porcine sodium heparin

• ammonia
• Carbomer 3500-6500
• Polyoxyethylene (6)-caprylic acid/capric acid glyceride
• perfume oil
• citral
• citronellol
• coumarin
• DL limonene
• eugenol
• farnesol
• geraniol
• linalool
• Polysorbate 60
• isopropanol
• water, purified

THROMBOPHOB Gel 60,000 heparin sodium indication

• For the supportive treatment of acute swelling after blunt injuries (bruises/bruising) and superficial phlebitis if this cannot be treated with compression.

THROMBOPHOB Gel 60,000 heparin sodium dosage

• Always use this medicine exactly as described or as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.

• The recommended dose is:
  • Apply thinly and evenly to the affected area 2 - 3 times a day.

• duration of use
  • The drug should not be used for more than 10 days.

• If you use more than you should
  • If you use more than you should, please contact your doctor or pharmacist.

• If you forgot the application
  • Do not apply a double dose to make up for a forgotten application.

• If you cancel the application
  • If you have any further questions on the use of this medicine, ask your doctor or pharmacist. If you want to interrupt the treatment or end it prematurely, please consult your doctor or pharmacist first.

   

THROMBOPHOB Gel 60,000 heparin sodium way

• Apply thinly and evenly to the affected area

side effects

• Like all medicines, this medicine can cause side effects, although not everybody gets them.
• The frequency information on side effects is based on the following categories:
  • Very common: affects more than 1 in 10 people
  • Common: affects 1 to 10 users in 100
  • Uncommon: affects 1 to 10 users in 1,000
  • Rare: affects 1 to 10 users in 10,000
  • Very rare: affects less than 1 in 10,000 people
  • Not known: frequency cannot be estimated from the available data
• Possible side effects:
  • Allergic reactions to heparin when applied to the skin are very rare. However, in individual cases, allergic reactions such as reddening of the skin and itching can occur, which usually disappear quickly after the preparation has been discontinued.
  • Blood and hematopoietic system
    • Not known: The frequency of occurrence of heparin-induced, antibody-mediated thrombocytopenia type II (decrease in platelet count < 100,000/µl or a rapid drop in platelet count to < 50% of baseline), with arterial and venous thrombosis or embolism, the can be fatal has not yet been investigated when applied locally to the skin. However, since the absorption of heparin through healthy skin after local application has been described, this risk cannot be ruled out with certainty. Increased attention is therefore indicated.
    • In patients without a history of hypersensitivity to heparin, the drop in blood platelet counts usually begins 6-14 days after the start of treatment. In patients with hypersensitivity to heparin, this decrease may occur within hours.
• What countermeasures should be taken in the event of side effects?
  • The drug should be discontinued if allergic skin reactions occur. Please inform your doctor about this. Apart from that, no further special measures are necessary.
• If you get any side effects, talk to your doctor or pharmacist. This also applies to side effects that are not specified.

THROMBOPHOB Gel 60,000 heparin sodium interactions

• When used with other medicines
  • Tell your doctor or pharmacist if you are taking/using, have recently taken/used or might take/use any other medicines.
  • Interactions with other medicinal products are not known in the case of topical application, but cannot be ruled out, particularly in the case of prolonged use, since penetration of heparin through healthy skin has been described.
  • Especially with drugs that interfere with blood clotting, such as platelet aggregation inhibitors (acetylsalicylic acid, ticlopidine, clopidogrel, dipyridamole in high doses), fibrinolytics, other anticoagulants (coumarin derivatives), non-steroidal anti-inflammatory drugs (phenylbutazone, indomethacin, sulfinpyrazone), glycoprotein IIb /IIa receptor antagonists, penicillin in high doses, dextrans, an increased risk of bleeding cannot be ruled out. Hematomas can occur more frequently or become worse.

Contraindications

• The medicine must not be used
  • if you are allergic to heparin or any of the other ingredients.
  • if you have an acute or a history of an allergic drop in the number of blood platelets (type II thrombocytopenia) caused by heparin.

pregnancy and breast feeding period

• Previous experience with the use of pregnant and lactating women has not yielded any indications of harmful effects.
• Heparin does not cross the placenta and does not pass into breast milk.
• If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before using this medicine.

patient THROMBOPHOB Gel 60,000 heparin sodium notes

• Particular caution in use is required
  • If new symptoms occur that may indicate thrombosis or pulmonary embolism, such as
    • swelling and warmth in the affected part of the body,
    • reddened and tense skin, possibly turning blue,
    • Feeling of tension and pain in the foot, calf and hollow of the knee (relief when lying up)
    • Sudden shortness of breath, chest pain and weakness/collapse
  • the presence of heparin-induced thrombocytopenia type II must be ruled out and the blood platelet count (thrombocyte count) must be checked immediately.
  • Regular checks of the platelet values ​​are necessary with every heparin application.
  • The platelet count should be checked:
    • before starting heparin administration
    • on the 1st day after the start of heparin administration
    • then every 3-4 days until the end of the heparin treatment
  • An increased risk of bleeding cannot be ruled out if drugs that interfere with blood clotting are used at the same time. Bruising may occur more frequently or increase in size.
  • During treatment, injections into the muscle should be avoided because of the risk of bruising (hematoma).
  • The medicinal product should not be applied to open wounds and/or weeping eczema.
  • The drug contains alcohol and should therefore not come into contact with the eyes or mucous membranes.
  • children and young people
    • Due to the lack of data on safety and effectiveness, the preparation is not
      recommended for use in children and adolescents under 18 years of age.

• Ability to drive and use machines
  • No restriction.