Neurobion N forte coated tablets
NEUROBION N forte Application:
Neurological systemic diseases due to a proven deficiency of vitamins B1 and B6
For risks and side effects, read the package insert and ask your doctor or pharmacist.
Against neurological systemic diseases caused by vitamin B1 and B6 deficiency.
Active ingredients
- 100 mg pyridoxine hydrochloride
- 100 mg thiamine disulfide
Excipients
- Magnesium stearate
- Hypromelosis
- Montan glycol wax
- Montan glycol wax
- Clay, whiter
- Silicon dioxide, highly disperse
- Butyl methacrylate copolymer, basic
- Povidone K25
- Magnesium oxide, light
- 152.7 mg sucrose
- Cornstarch
- Lactose-1-water
- Methylcellulose
- Titanium dioxide
- Glycerol 85%
- Calcium carbonate
Indication :
- The medicine is a vitamin B 1 + B 6 preparation against neurological diseases.
- It is used for neurological systemic diseases due to a proven deficiency of vitamins B 1 and B 6 .
Dosage :
- Always take this medicine exactly as described or as directed by your doctor. Check with your doctor or pharmacist if you are unsure.
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The recommended dose is:
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Adult
- Unless otherwise prescribed, adults take one coated tablet once daily.
- If there is a manifest, proven deficiency, the dose can be increased to up to one coated tablet 3 times a day after consulting your doctor.
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Adult
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Duration of application
- After 4 weeks at the latest, your treating doctor should decide whether administration of vitamin B 6 and vitamin B 1 in the high concentration present is still necessary.
- If necessary, your doctor will switch you to a preparation with a lower strength of active ingredient to reduce the risk of neuropathy (risk of nerve damage) associated with vitamin B 6 .
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If you have taken more than you should
- Long-term use (months to years) of vitamin B 6 in doses above 50 mg/day and short-term use (2 months) in doses above 1g/day can lead to nerve damage.
- An overdose is essentially manifested by abnormal sensations such as tingling or pins and needles on the hands and feet (sensory polyneuropathies), possibly with movement disorders (ataxia). Extremely high doses can result in convulsions.
- If doses over 150 mg/kg body weight have been taken acutely, artificially induced vomiting and the administration of activated charcoal are recommended. Vomiting is most effective in the first 30 minutes after ingestion. Intensive care measures may be necessary.
- High doses of vitamin B 6 can inhibit milk production during breastfeeding.
- If physical symptoms occur, you should consult a doctor.
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If you forget to take it
- Do not take a double dose if you forget to take the previous dose. Continue taking as described in the dosage instructions.
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If you stop taking it
- For successful treatment, it is important that you take the medicine for the entire period recommended by your doctor.
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If you have any further questions about taking this medicine, talk to your doctor or pharmacist.
Way :
- To take.
- Take the coated tablets whole with sufficient liquid (e.g. 1 glass of water) before or after meals.
Side effects :
- Like all medicines, this medicine can cause side effects, although not everyone gets them.
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If you experience any of the side effects listed below, stop taking the medicine and contact your doctor as soon as possible.
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Very rare side effects (may affect up to 1 in 10,000 people)
- Hypersensitivity reactions such as sweating, rapid heartbeat, skin reactions with itching and hives after taking thiamine (vitamin B 1 ).
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Not known (frequency cannot be estimated from available data)
- Gastrointestinal complaints such as nausea, vomiting, diarrhea and abdominal discomfort.
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Not known (frequency cannot be estimated from available data):
- Long-term overdose of vitamin B 6 (longer than 2 months with an intake of more than 1g/day) can cause nerve-damaging effects. Long-term intake (more than 6 - 12 months) of daily doses of more than 50 mg of vitamin B 6 can cause abnormal sensations, primarily in the hands and feet (peripheral sensory neuropathy).
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Very rare side effects (may affect up to 1 in 10,000 people)
- If you notice any side effects, contact your doctor, pharmacist or nurse. This also applies to side effects that are not specified.
Interactions :
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Taking together with other medicines
- Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines, including medicines obtained without a prescription.
- Therapeutic doses of vitamin B6 can weaken the effects of the antiparkinsonian drug L-dopa.
- The simultaneous administration of so-called pyridoxine antagonists (medicines that have, among other things, an effect directed against vitamin B 6 , such as hydralazine (medicine for the treatment of high blood pressure), isoniazid (INH) (antibiotic), cycloserine (antibiotic), D-penicillamine (medicine for Treatment of rheumatic diseases)) can increase the need for vitamin B 6 .
- The medicine loses its effect when the cancer drug (cytostatic) 5-fluorouracil is administered at the same time.
- Taking medicines that bind stomach acid at the same time reduces the absorption of vitamin B1 .
- Long-term treatment with the diuretic furosemide can result in a vitamin B1 deficiency because increased amounts of vitamin B1 are excreted in the urine.
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Take with food, drinks and alcohol
- Vitamin B 1 can be broken down and therefore become ineffective if drinks containing sulfite are consumed at the same time, such as wine.
- Alcohol and black tea reduce the absorption of vitamin B1 .
- Therefore, do not drink alcohol or black tea while being treated with this medicine.
Contraindications :
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The medicine must not be taken
- if you are allergic to thiamine disulfide (vitamin B 1 ), pyridoxine hydrochloride (vitamin B 6 ) or any of the other ingredients of this medicine.
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of children and young people under 18 years of age
- The medicine must not be taken by children and adolescents due to the high active ingredient content.
Pregnancy and breast feeding period :
- If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
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pregnancy
- There are no sufficient study data on pregnant women who were treated with high doses of vitamin B 1 or B 6 .
- During pregnancy, the recommended total daily intake for vitamin B 1 is 1.2 mg/day (2nd trimester) or 1.3 mg/day (3rd trimester) and for vitamin B 6 1.9 mg/day. These dosages may only be exceeded during pregnancy if there is a proven vitamin B 1 and B 6 deficiency. Vitamin B 1 and B 6 pass into the placenta.
- The use of this medicine during pregnancy should only be decided after careful benefit/risk assessment by your treating doctor.
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lactation
- Vitamin B 1 and B 6 are excreted in breast milk. During breastfeeding, the recommended total daily intake of vitamin B 1 for the mother is 1.4 mg/day and vitamin B 6 is 2 mg/day. High doses of vitamin B 6 can inhibit milk production.
- The use of this medicine during breastfeeding should only be decided by your treating doctor after careful risk/benefit assessment.
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reproductive ability
- There are no sufficient study data on humans.
Patient information :
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Warnings and Precautions
- Please talk to your doctor or pharmacist before taking the medicine.
- Even in daily doses of 50 mg or more over a long period of time (months to years), vitamin B 6 can cause nerve damage (neuropathies), which are manifested by signs such as tingling and pins and needles in the hands and feet (signs of peripheral sensory neuropathy or paresthesia). can. If you notice tingling and pins and needles, please contact your doctor.
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Ability to drive and use machines
- The medicine has no or negligible influence on the ability to drive and use machines.